Kerns Mary Jo, Stinehelfer Susan, Mutasim Diya F, Zalla Mark J
University of Cincinnati, Cincinnati, Ohio 45267-0592, USA.
Pediatr Dermatol. 2011 Mar-Apr;28(2):142-5. doi: 10.1111/j.1525-1470.2010.01218.x.
Annular lipoatrophy of the ankles also termed "annular atrophic connective tissue panniculitis of the ankles,""annular atrophy of the ankles," and "atrophic annular panniculitis of the ankles," is an inflammatory panniculitis that results in lipoatrophy with a predilection for the ankles. The disorder is seen predominantly in female children and demonstrates a mixed lobular panniculitis. It is likely a disorder of autoimmune etiology, supported by the findings of concurrent autoimmune disorders in several patients. We report a case of a 6-year-old female with annular lipoatrophy of the ankles associated with Hashimoto thyroiditis and review the epidemiology and proposed pathogenesis of annular lipoatrophy of the ankles.
脚踝部环状脂肪萎缩，也被称为“脚踝部环状萎缩性结缔组织性脂膜炎”“脚踝部环状萎缩”以及“脚踝部萎缩性环状脂膜炎”，是一种炎症性脂膜炎，可导致脂肪萎缩，好发于脚踝部。该病症主要见于女童，表现为混合性小叶性脂膜炎。鉴于数例患者同时存在自身免疫性疾病的情况，它很可能是一种自身免疫病因的病症。我们报告一例6岁患脚踝部环状脂肪萎缩并伴有桥本甲状腺炎的女性病例，并回顾脚踝部环状脂肪萎缩的流行病学及推测的发病机制。
