Laboratoire de Spectrochimie Infrarouge et Raman, LASIR, CNRS UMR 8516, Bât. C5, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq Cedex, France.
Anal Chim Acta. 2010 Aug 3;674(2):220-6. doi: 10.1016/j.aca.2010.06.025. Epub 2010 Jul 1.
Chemical imaging systems help to solve many challenges in various scientific fields. Able to deliver rapid spatial and chemical information, modern infrared spectrometers using Focal Plane Array detectors (FPA) are of great interest. Considering conventional infrared spectrometers with a single element detector, we can consider that the diffraction-limited spatial resolution is more or less equal to the wavelength of the light (i.e. 2.5-25 microm). Unfortunately, the spatial resolution of FPA spectroscopic setup is even lower due to the detector pixel size. This becomes a real constraint when micron-sized samples are analysed. New chemometrics methods are thus of great interest to overcome such resolution drawback, while keeping our far-field infrared imaging spectrometers. The aim of the present work is to evaluate the super-resolution concept in order to increase the spatial resolution of infrared imaging spectrometers using FPA detectors. The main idea of super-resolution is the fusion of several low-resolution images of the same sample to obtain a higher-resolution image. Applying the super-resolution concept on a relatively low number of FPA acquisitions, it was possible to observe a 30% decrease in spatial resolution.
化学成像系统有助于解决各个科学领域的许多挑战。使用焦平面阵列探测器（FPA）的现代红外光谱仪能够快速提供空间和化学信息，因此备受关注。考虑到具有单个元件探测器的传统红外光谱仪，我们可以认为衍射极限空间分辨率或多或少等于光的波长（即 2.5-25 微米）。不幸的是，由于探测器像素尺寸，FPA 光谱仪设置的空间分辨率甚至更低。当分析微米大小的样品时，这就成为了一个真正的限制。因此，新的化学计量学方法对于克服这种分辨率缺陷非常有吸引力，同时保持我们的远场红外成像光谱仪。本工作的目的是评估超分辨率概念，以提高使用 FPA 探测器的红外成像光谱仪的空间分辨率。超分辨率的主要思想是融合同一样品的几个低分辨率图像以获得更高分辨率的图像。在相对较少的 FPA 采集次数上应用超分辨率概念，可以观察到空间分辨率降低 30%。
