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青年期精神障碍的负担与 30 岁时的生活结局。

Burden of psychiatric disorder in young adulthood and life outcomes at age 30.

机构信息

Christchurch Health and Development Study, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

出版信息

Br J Psychiatry. 2010 Aug;197(2):122-7. doi: 10.1192/bjp.bp.109.076570.

DOI:10.1192/bjp.bp.109.076570
PMID:20679264
Abstract

BACKGROUND

Psychiatric disorders are common during young adulthood and comorbidity is frequent. Individual psychiatric disorders have been shown to be associated with negative economic and educational outcomes, but few studies have addressed the relationship between the total extent of psychiatric disorder and life outcomes.

AIMS

To examine whether the extent of common psychiatric disorder between ages 18 and 25 is associated with negative economic and educational outcomes at age 30, before and after controlling for confounding factors.

METHOD

Participants were 987 individuals from the Christchurch Health and Development Study, a longitudinal study of a birth cohort of individuals born in Christchurch, New Zealand, in 1977 and followed to age 30. Linear and logistic regression models were used to examine the associations between psychiatric disorder from age 18 to 25 and workforce participation, income and living standards, and educational achievement at age 30, before and after adjustment for confounding factors.

RESULTS

There were significant associations between the extent of psychiatric disorder reported between ages 18 and 25 and all of the outcome measures (all P<0.05). After adjustment for confounding factors, the associations between psychiatric disorder and workforce participation, income and living standards remained significant (all P<0.05), but the associations between psychiatric disorder and educational achievement were not significant (all P>0.10).

CONCLUSIONS

After due allowance had been made for a range of confounding factors, psychiatric disorder between ages 18 and 25 was associated with reduced workforce participation, lower income and lower economic living standards at age 30.

摘要

背景

精神障碍在青年期很常见,且常伴有共病。已有研究表明,个体精神障碍与负面的经济和教育结果相关,但很少有研究关注精神障碍的总严重程度与生活结果之间的关系。

目的

探究 18 至 25 岁之间常见精神障碍的严重程度是否与 30 岁时的负面经济和教育结果相关,以及在控制混杂因素前后的关系。

方法

参与者为基督城健康与发展研究中的 987 名个体,这是一项对 1977 年在新西兰基督城出生的队列个体进行的纵向研究,随访至 30 岁。线性和逻辑回归模型用于检验从 18 岁至 25 岁期间的精神障碍与 30 岁时的劳动力参与、收入和生活水平以及教育成就之间的关联,在调整混杂因素之前和之后进行分析。

结果

18 至 25 岁之间报告的精神障碍严重程度与所有结局指标均显著相关(均 P<0.05)。在调整混杂因素后,精神障碍与劳动力参与、收入和生活水平之间的关联仍然显著(均 P<0.05),但与教育成就之间的关联不再显著(均 P>0.10)。

结论

在充分考虑了一系列混杂因素后,18 至 25 岁之间的精神障碍与 30 岁时劳动力参与减少、收入降低和经济生活水平较低相关。

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