Department of Neurosurgery, Tufts Medical Center, Boston, Massachusetts, USA.
Neurosurgery. 2010 Sep;67(3 Suppl Operative):ons300-3; discussion ons303. doi: 10.1227/01.NEU.0000383876.72704.7B.
Indocyanine green (ICG) fluorescence videography has been recently applied to the neurosurgical field, mostly in the management of cerebral aneurysms, but has had limited description in the subspecialty of spine or oncological neurosurgery. We describe a novel application of this previously defined surgical tool to assist in the resection of a residual spinal cord hemangioblastoma.
Our patient is a 49-year-old woman with a residual symptomatic cervical hemangioblastoma that was previously embolized and resected at another institution. After initial symptomatic improvement, she returned with progressive symptoms, increasing radiographic spinal cord edema, and a residual lesion at the level of C1. We resected the remaining tumor with the adjuvant use of ICG fluorescence videography. Intraoperative injection of ICG clearly identified a component of the tumor underlying adhesive, opaque arachnoid that was not visualized by direct microscopy. Immediate postresection ICG videography suggested a complete resection was achieved which was later corroborated by postoperative magnetic resonance imaging.
The adjuvant use of ICG videography is a useful surgical tool that permits greater visualization of the complete extent of the lesion, particularly in managing recurrent or residual lesions obscured by adhesions.
吲哚菁绿(ICG)荧光摄像术最近已应用于神经外科领域,主要用于脑动脉瘤的治疗,但在脊柱或肿瘤神经外科领域的描述有限。我们描述了一种新的应用方法,用于辅助切除残留的脊髓血管母细胞瘤。
我们的患者是一位 49 岁的女性,曾在另一家医院接受过栓塞和切除治疗,但仍有残留的颈脊髓血管母细胞瘤。在最初的症状改善后,她出现了进行性的症状加重、放射影像学脊髓水肿加重,且 C1 水平仍存在残留病变。我们使用 ICG 荧光摄像术辅助切除了剩余肿瘤。术中 ICG 注射可清楚地识别出肿瘤的一个成分,该成分位于粘连、不透明的蛛网膜下,直接显微镜观察不到。术后即刻 ICG 摄像显示肿瘤已完全切除,术后磁共振成像也证实了这一点。
ICG 摄像术的辅助应用是一种有用的手术工具,可更好地观察病变的完整范围,特别是在处理因粘连而被掩盖的复发性或残留病变时。