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[采用恒定胸周负压治疗新生儿特发性呼吸窘迫重症形式]

[Treatment of severe forms of idiopathic respiratory distress in newborn infants using constant negative perithoracic pressure].

作者信息

Salle B

出版信息

Ann Anesthesiol Fr. 1975;16 Spec No 1:105-17.

PMID:2068
Abstract

49 children with a severe idiopathic respiratory distress syndrome were treated by continuous negative pressure ranging from 5 cm of water to a negative pressure of 13 cm of water around the thorax. The partial pressure of oxygen rose significantly in the majority of cases, and the alveolo-arterial gradient also significantly diminished by more than 100 mm of mercury. 29 children were treated by this method alone, but in 20 other children owing to the failure of constant negative pressure, respiratory assistance either by intermittent pressure ventilation or intermittent positive pressure ventilation was associated. On the whole 35 out of 49 children survived. The complications which were met with are analyzed. Continuous negative pressure seems to be a safe and effective method for improving oxygenation in the idiopathic respiratory distress syndrome.

摘要

对49名患有严重特发性呼吸窘迫综合征的儿童,采用围绕胸部5厘米水柱至13厘米水柱的持续负压进行治疗。大多数病例中氧分压显著上升,肺泡 - 动脉血氧分压差也显著降低超过100毫米汞柱。29名儿童仅采用此方法治疗,但另外20名儿童由于持续负压治疗失败,联合采用了间歇压力通气或间歇正压通气进行呼吸辅助。总体而言,49名儿童中有35名存活。对所遇到的并发症进行了分析。持续负压似乎是改善特发性呼吸窘迫综合征氧合的一种安全有效的方法。

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