Mannion Anne F, Denzler R, Dvorak J, Grob D
Spine Center Division, Schulthess Klinik, Lengghalde 2, 8008 Zurich, Switzerland.
Eur Spine J. 2010 Nov;19(11):1883-91. doi: 10.1007/s00586-010-1535-2. Epub 2010 Jul 31.
As the average life expectancy of the population increases, surgical decompression of the lumbar spine is being performed with increasing frequency. It now constitutes the most common type of lumbar spinal surgery in older patients. The present prospective study examined the 5-year outcome of lumbar decompression surgery without fusion. The group comprised 159 patients undergoing decompression for degenerative spinal disorders who had been participants in a randomised controlled trial of post-operative rehabilitation that had shown no between-group differences at 2 years. Leg pain and back pain intensity (0-10 graphic rating scale), self-rated disability (Roland Morris), global outcome of surgery (5-point Likert scale) and re-operation rates were assessed 5 years post-operatively. Ten patients had died before the 5-year follow-up. Of the remaining 149 patients, 143 returned a 5-year follow-up (FU) questionnaire (effective return rate excluding deaths, 96%). Their mean age was 64 (SD 11) years and 92/143 (64%) were men. In the 5-year follow-up period, 34/143 patients (24%) underwent re-operation (17 further decompressions, 17 fusions and 1 intradural drainage/debridement). In patients who were not re-operated, leg pain decreased significantly (p < 0.05) from before surgery to 2 months FU, after which there was no significant change up to 5 years. Low back pain also decreased significantly by 2 months FU, but then showed a slight, but significant (p < 0.05), gradual increase of <1 point by 5-year FU. Disability decreased significantly from pre-operative to 2 months FU and showed a further significant decrease at 5 months FU. Thereafter, it remained stable up to the 5-year FU. Pain and disability scores recorded after 5 years showed a significant correlation with those at earlier follow-ups (r = 0.53-0.82; p < 0.05). Patients who were re-operated at some stage over the 5-year period showed significantly worse final outcomes for leg pain and disability (p < 0.05). In conclusion, pain and disability showed minimal change in the 5-year period after surgery, but the re-operation rate was relatively high. Re-operation resulted in worse final outcomes in terms of leg pain and disability. At the 5-year follow-up, the "average" patient experienced frequent, but relatively low levels of, pain and moderate disability. This knowledge on the long-term outcome should be incorporated into the pre-operative patient information process.
随着人口平均预期寿命的增加,腰椎手术减压的频率越来越高。现在,它已成为老年患者中最常见的腰椎手术类型。本前瞻性研究考察了非融合腰椎减压手术的5年疗效。该组包括159例因退行性脊柱疾病接受减压手术的患者,他们曾参与一项术后康复的随机对照试验,该试验显示2年时组间无差异。在术后5年评估腿痛和背痛强度(0 - 10视觉模拟评分量表)、自评残疾程度(罗兰·莫里斯量表)、手术总体疗效(5级李克特量表)和再次手术率。10例患者在5年随访前死亡。在其余149例患者中,143例返回了5年随访(FU)问卷(排除死亡后的有效回收率为96%)。他们的平均年龄为64(标准差11)岁,143例中有92例(64%)为男性。在5年随访期内,143例患者中有34例(24%)接受了再次手术(17例进一步减压、17例融合手术和1例硬膜内引流/清创术)。未接受再次手术的患者,腿痛从术前到随访2个月时显著减轻(p < 0.05),此后直至5年无显著变化。腰痛在随访2个月时也显著减轻,但随后在5年随访时出现轻微但显著(p < ......