Mulsow J, Jeffers M, McDermott R, Geraghty J, Rothwell J
Department of Surgery, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland.
Thorac Cardiovasc Surg. 2010 Aug;58(5):306-8. doi: 10.1055/s-0029-1186198. Epub 2010 Aug 2.
Askin tumor is a tumor of the thoracopulmonary region that most commonly affects children and adolescents. These rare tumors are a form of primitive neuroectodermal tumor and typically carry a poor prognosis. Treatment is multimodal and consists of a combination of neoadjuvant chemotherapy, radical resection, and adjuvant chemo- and radiotherapy or all of the above. Surgery is advocated in most cases. We report a case of Askin tumor in a 54-year-old male who showed rapid and complete response to neoadjuvant chemotherapy. This allowed potentially radical surgery to be avoided. At one-year follow-up he remains disease-free.
Askin瘤是一种发生于胸肺区域的肿瘤，最常见于儿童和青少年。这些罕见肿瘤是原始神经外胚层肿瘤的一种形式，通常预后较差。治疗采用多模式，包括新辅助化疗、根治性切除以及辅助化疗和放疗，或上述所有方法的联合。大多数情况下提倡手术治疗。我们报告一例54岁男性Askin瘤患者，该患者对新辅助化疗表现出快速且完全的反应。这使得有可能避免进行根治性手术。在一年的随访中，他仍无疾病复发。
