MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, UK.
Evid Based Ment Health. 2010 Aug;13(3):65-8. doi: 10.1136/ebmh.13.3.65.
Misunderstandings surrounding the study of gene-environment interactions are very common. Given the large increase in the number of studies examining interactions in recent years, this raises serious concerns about the value of time and resources spent in these endeavours. In this article we discuss why, despite frequent claims to the contrary, studies of gene-environment interactions are very unlikely to enhance our understanding of disease aetiology or prevention.
围绕基因-环境相互作用的研究存在很多误解。鉴于近年来研究相互作用的数量大量增加,这引发了对在这些努力中投入的时间和资源的价值的严重关注。在本文中,我们讨论了为什么尽管经常有相反的说法,但对基因-环境相互作用的研究不太可能增强我们对疾病病因或预防的理解。