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利多卡因喷雾是否可用于减轻鼻胃管插入的不适?一项双盲、随机对照试验。

Should lidocaine spray be used to ease nasogastric tube insertion? A double-blind, randomised controlled trial.

机构信息

St Teresa's Hospital, Prince Edward Road, Hong Kong.

出版信息

Hong Kong Med J. 2010 Aug;16(4):282-6.

PMID:20683071
Abstract

OBJECTIVE

To investigate the efficacy and safety of lidocaine nasal spray before nasogastric tube insertion in an emergency department.

DESIGN

Double-blind, randomised controlled study.

SETTING

Emergency department of a major regional hospital in Hong Kong.

PATIENTS

A total of 206 adult patients, for whom nasogastric tube insertion was indicated.

MAIN OUTCOME MEASURES

Primary outcome was discomfort gauged on a visual analogue scale, and Likert scale addressing difficulty of nasogastric tube insertion.

RESULTS

Compared with placebo spray use, lidocaine spray use was associated with less patient discomfort, and less difficulty in nasogastric tube insertion, both difference being statistically significant.

CONCLUSION

Intranasal lidocaine spray before nasogastric tube insertion was safe and effective in reducing patient discomfort related to the procedure.

摘要

目的

研究在急诊科中使用利多卡因鼻喷雾剂在进行鼻胃管插入前的疗效和安全性。

设计

双盲、随机对照研究。

地点

香港一家主要地区医院的急诊科。

患者

共有 206 名成年患者,他们需要进行鼻胃管插入。

主要观察指标

主要结局指标是使用视觉模拟评分法评估的不适程度,以及使用李克特量表评估的鼻胃管插入难度。

结果

与使用安慰剂喷雾相比,利多卡因喷雾使用后患者的不适程度较低,且鼻胃管插入的难度也较低,这两个差异均具有统计学意义。

结论

在鼻胃管插入前使用鼻内利多卡因喷雾是安全有效的,可以减轻与该操作相关的患者不适。

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引用本文的文献

1
Effectiveness of Lidocaine nasal drops versus placebo drops for reducing the discomfort of nasogastric tube insertion: a randomized controlled trial study.利多卡因滴鼻剂与安慰剂滴鼻剂减轻鼻胃管插入不适的效果比较:一项随机对照试验研究。
Surg Today. 2024 Jun;54(6):591-595. doi: 10.1007/s00595-023-02768-9. Epub 2023 Nov 22.
2
The application of lidocaine to alleviate the discomfort of nasogastric tube insertion: A systematic review and meta-analysis.利多卡因用于减轻鼻胃管插入不适的应用:一项系统评价和荟萃分析。
Medicine (Baltimore). 2018 Feb;97(5):e9746. doi: 10.1097/MD.0000000000009746.