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香港人类布鲁氏菌病的诊断挑战:两家地区医院的病例系列。

Diagnostic challenges of human brucellosis in Hong Kong: a case series in two regional hospitals.

机构信息

Department of Pathology, Princess Margaret Hospital, Laichikok, Hong Kong.

出版信息

Hong Kong Med J. 2010 Aug;16(4):299-303.

PMID:20683074
Abstract

A retrospective analysis of six patients diagnosed with brucellosis in two regional hospitals was carried out. The epidemiological, clinical, and laboratory features were studied. All patients had exposure history. Three patients presented with musculoskeletal symptoms, while three had predominantly genitourinary symptoms. One patient did not have fever at presentation. All patients were diagnosed by positive blood culture of Brucella melitensis, and the diagnosis was not suspected for all except one patient at presentation. Given the inferior sensitivity of blood culture to serology, human brucellosis may be underdiagnosed, especially when the index of suspicion is low.

摘要

对两家地区医院诊断的 6 例布氏杆菌病患者进行了回顾性分析。研究了其流行病学、临床和实验室特征。所有患者均有接触史。3 例患者表现为肌肉骨骼症状,3 例主要为泌尿生殖系统症状。1 例患者就诊时无发热。所有患者均通过布鲁氏菌 melitensis 阳性血培养诊断,除 1 例患者外,就诊时均未怀疑该诊断。鉴于血培养对血清学的敏感性较低,人类布鲁氏菌病的诊断可能不足,尤其是在怀疑指数较低时。

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Diagnostic challenges of human brucellosis in Hong Kong: a case series in two regional hospitals.香港人类布鲁氏菌病的诊断挑战:两家地区医院的病例系列。
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Long ignored but making a comeback: a worldwide epidemiological evolution of human brucellosis.长期被忽视但正在卷土重来:人类布鲁氏菌病的全球流行病学演变
Emerg Microbes Infect. 2024 Dec;13(1):2290839. doi: 10.1080/22221751.2023.2290839. Epub 2024 Feb 19.
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Acute Brucellosis and Cirrhosis: The Triggering Event of Fatal Liver Decompensation.急性布鲁氏菌病与肝硬化:致命性肝失代偿的触发事件
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Laboratory Diagnosis of Human Brucellosis.人布鲁氏菌病的实验室诊断。
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Human brucellosis mimicking axial spondyloarthritis: a challenge for rheumatologists when applying the 2009 ASAS criteria.酷似中轴型脊柱关节炎的人类布鲁氏菌病:对风湿科医生应用2009年ASAS标准而言是一项挑战。
J Huazhong Univ Sci Technolog Med Sci. 2016 Jun;36(3):368-371. doi: 10.1007/s11596-016-1593-8. Epub 2016 Jul 5.
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Increasing threat of brucellosis to low-risk persons in urban settings, China.中国城市环境中低风险人群布鲁氏菌病威胁增加。
Emerg Infect Dis. 2014 Jan;20(1):126-30. doi: 10.3201/eid2001.130324.