Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan 48109-0048, USA.
Eur J Anaesthesiol. 2010 Dec;27(12):1065-8. doi: 10.1097/EJA.0b013e32833cfd8d.
childhood obesity is a risk factor for many perioperative complications. Hypotension is a well described complication of general anaesthesia in both adults and children. This observational study compared the incidence of preincision hypotension (PIH) between children with high BMI and lean controls.
children aged 2-17 years undergoing noncardiac procedures were classified into high or normal BMI groups. The incidence of PIH was then compared between the two groups using SBP data abstracted from our electronic anaesthesia monitoring system. Binary logistic regression was used to examine factors associated with the likelihood of PIH.
the study population was 19 400 children (54% boys) with a mean (SD) age of 8.3 ± 4.7 years and BMI of 19.3 ± 5.7 kg m(-2). Most (94.7%) of the patients were elective American Society of Anesthesiology I-II (79.7%) procedures. Single episode of PIH occurred in 36.8% of patients, whereas 8.3% had at least three episodes of PIH. PIH was more frequent in children with high BMI than their lean peers (40.9 vs. 31.4%, P < 0.001). Independent predictors of PIH were high BMI, high American Society of Anesthesiology status, propofol coinduction, baseline hypotension, age and preincision duration.
these results imply that children with high BMI have a higher incidence of hypotension than their lean peers following induction of anaesthesia for noncardiac procedures.
儿童肥胖是许多围手术期并发症的危险因素。低血压是成人和儿童全身麻醉中一种常见的并发症。本观察性研究比较了高 BMI 儿童和瘦对照组之间术前低血压(PIH)的发生率。
将 2-17 岁接受非心脏手术的儿童分为高 BMI 组或正常 BMI 组。然后使用从我们的电子麻醉监测系统中提取的 SBP 数据比较两组之间 PIH 的发生率。使用二项逻辑回归检查与 PIH 发生可能性相关的因素。
研究人群为 19400 名儿童(54%为男孩),平均(SD)年龄为 8.3 ± 4.7 岁,BMI 为 19.3 ± 5.7 kg/m²。大多数(94.7%)患者为美国麻醉医师协会 I-II 级(79.7%)择期手术。36.8%的患者出现单次 PIH,8.3%的患者出现至少三次 PIH。高 BMI 儿童比瘦对照组发生 PIH 的频率更高(40.9%比 31.4%,P < 0.001)。PIH 的独立预测因素包括高 BMI、高美国麻醉医师协会状态、异丙酚联合诱导、基线低血压、年龄和术前持续时间。
这些结果表明,与瘦对照组相比,非心脏手术麻醉诱导后,高 BMI 儿童发生低血压的发生率更高。