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头臂型血液透析动静脉内瘘的通路血流量减少及复发性症状性头臂动脉弓狭窄

Access flow reduction and recurrent symptomatic cephalic arch stenosis in brachiocephalic hemodialysis arteriovenous fistulas.

作者信息

Miller Gregg Arthur, Friedman Alexander, Khariton Aleksandr, Preddie Dean C, Savransky Yevgeny

机构信息

American Access Care of Brooklyn, NY 11215, USA.

出版信息

J Vasc Access. 2010 Oct-Dec;11(4):281-7. doi: 10.5301/jva.2010.592.

Abstract

BACKGROUND

Recurrent cephalic arch stenosis (CAS) has been linked to high flow and has a high rate of recurrence following angioplasty. This study investigates the effectiveness of access flow reduction in decreasing rapidly recurrent symptomatic CAS.

METHODS

A retrospective study of patient records from February 2005 to April 2009 was conducted. Patients with brachiocephalic fistulas who had undergone two or more instances of cephalic arch angioplasty within 3 months, and thereafter underwent flow reduction via banding of the access inflow (n=33) were included. A before-and-after analysis was conducted: the rates of cephalic arch angioplasty were calculated for each patient before and after the banding procedure, and compared via a paired t-test.

RESULTS

At 3, 6, and 12 months, the cephalic arch primary lesion patency was 91%, 76%, and 57%. The cephalic arch intervention rate was reduced from 3.34 to 0.9 per access-year (t=7.74, p<.001). The average follow-up time was 14.5 months (range, 4.8-32).

CONCLUSION

Flow reduction of a brachiocephalic arteriovenous hemodialysis fistula may effectively diminish the incidence of symptomatic CAS.

摘要

背景

复发性头臂动脉弓狭窄(CAS)与高血流量相关,且血管成形术后复发率高。本研究调查了减少通路血流量对降低快速复发的有症状CAS的有效性。

方法

对2005年2月至2009年4月的患者记录进行回顾性研究。纳入了接受头臂动静脉内瘘手术且在3个月内进行了两次或更多次头臂动脉弓血管成形术,随后通过绑扎通路流入端进行血流量减少治疗的患者(n = 33)。进行前后分析:计算每个患者在绑扎手术前后的头臂动脉弓血管成形术发生率,并通过配对t检验进行比较。

结果

在3个月、6个月和12个月时,头臂动脉弓原发性病变通畅率分别为91%、76%和57%。头臂动脉弓干预率从每个通路每年3.34次降至0.9次(t = 7.74,p <.001)。平均随访时间为14.5个月(范围4.8 - 32个月)。

结论

头臂动静脉血液透析内瘘的血流量减少可能有效降低有症状CAS的发生率。

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