妊娠相关肾病的管理。

Management of renal disease in pregnancy.

机构信息

Division of Nephrology, McGill University, 687 Pine Avenue West Ross 2.38, Montreal, QC H3A 1A1, Canada.

出版信息

Obstet Gynecol Clin North Am. 2010 Jun;37(2):195-210. doi: 10.1016/j.ogc.2010.02.012.

DOI:10.1016/j.ogc.2010.02.012

PMID:20685548

Abstract

Although renal disease in pregnancy is uncommon, it poses considerable risk to maternal and fetal health. This article discusses renal physiology and assessment of renal function in pregnancy and the effect of pregnancy on renal disease in patients with diabetes, lupus, chronic glomerulonephritis, polycystic kidney disease, and chronic pyelonephritis. Renal diseases occasionally present for the first time in pregnancy, and diagnoses of glomerulonephritis, acute tubular necrosis, hemolytic uremic syndrome, and acute fatty liver of pregnancy are described. Finally, therapy of end-stage renal disease in pregnancy, dialysis, and renal transplantation are reviewed.

摘要

尽管妊娠合并肾脏疾病并不常见，但它会给母婴健康带来相当大的风险。本文讨论了妊娠期间的肾脏生理学和肾功能评估，以及妊娠对糖尿病、狼疮、慢性肾小球肾炎、多囊肾病和慢性肾盂肾炎患者肾脏疾病的影响。肾脏疾病有时也会首次在妊娠期间出现，文中还描述了肾小球肾炎、急性肾小管坏死、溶血尿毒综合征和妊娠急性脂肪肝的诊断。最后，还回顾了妊娠终末期肾病的治疗、透析和肾移植。