[The correlation of the indices of humoral immunity and of the activity of the renin-angiotensin-aldosterone system in hypertensive patients].

The content of IgA, IgM, IgG and IgE was measured in 55 male patients with uncomplicated essential hypertension (EH) running a labile course (25 patients) and a stable course (30 patients). Analyzing the material, account was taken of aggravated heredity factor as regards arterial hypertension, established according to the anamnesis in relatives of the first degree kinship. A group of patients with the aggravated familial anamnesis as regards arterial hypertension were distinguished. They suffered from labile hypertension with a tendency to hyperreninemia and IgE overproduction, which may be unfavourable in terms of EH progression and development of cardiovascular complications.