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[高血压患者体液免疫指标与肾素 - 血管紧张素 - 醛固酮系统活性的相关性]

[The correlation of the indices of humoral immunity and of the activity of the renin-angiotensin-aldosterone system in hypertensive patients].

作者信息

Vil'chinskaia M Iu, Zharova E A, Nasonov E L, Bosykh E G

出版信息

Ter Arkh. 1991;63(4):54-8.

PMID:2068680
Abstract

The content of IgA, IgM, IgG and IgE was measured in 55 male patients with uncomplicated essential hypertension (EH) running a labile course (25 patients) and a stable course (30 patients). Analyzing the material, account was taken of aggravated heredity factor as regards arterial hypertension, established according to the anamnesis in relatives of the first degree kinship. A group of patients with the aggravated familial anamnesis as regards arterial hypertension were distinguished. They suffered from labile hypertension with a tendency to hyperreninemia and IgE overproduction, which may be unfavourable in terms of EH progression and development of cardiovascular complications.

摘要

对55例患有单纯性原发性高血压(EH)且病情不稳定(25例)和病情稳定(30例)的男性患者进行了IgA、IgM、IgG和IgE含量的测定。在分析这些资料时,考虑了根据一级亲属的病史确定的动脉高血压加重遗传因素。区分出一组动脉高血压家族病史加重的患者。他们患有不稳定型高血压,有高肾素血症和IgE产生过多的倾向,这在EH进展和心血管并发症的发生方面可能是不利的。

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