Vil'chinskaia M Iu, Nasonov E L, Shkhvatsabaia I K, Zharova E A, Gracheva L A
Klin Med (Mosk). 1989 Mar;67(3):51-4.
Examination included 51 patients with essential hypertension (EH) of an uncomplicated course, labile (IB-IIA stage, according to A. L. Myasnikov's classification) and stable (IIB stage) hypertension. Clinical characteristics were given to the stages and duration of EH, body weight of the patients, arterial hypertension (AH) heredity and the AP level. Immunological examination included determination of the concentration of the basic classes of immunoglobulins IgG, IgA, IgM, circulating immune complexes (CIC), concentration of IgE and beta 2-microglobulins. It was revealed that EH development is attended by an increased concentration of immunoglobulins, primarily of IgA (23 per cent), IgE (31 per cent) and CIC (21 per cent), which is associated, to a certain degree, with a factor of AH hereditary aggravation.
研究对象包括51例病程无并发症的原发性高血压（EH）患者，其中血压波动型（根据A.L.米亚斯尼科夫分类为IB-IIA期）和稳定型（IIB期）高血压患者。给出了EH的分期和病程、患者体重、动脉高血压（AH）遗传情况及血压水平的临床特征。免疫学检查包括测定免疫球蛋白IgG、IgA、IgM的基础类别浓度、循环免疫复合物（CIC）、IgE浓度和β2-微球蛋白。结果显示，EH的发生伴随着免疫球蛋白浓度升高，主要是IgA（23%）、IgE（31%）和CIC（21%），这在一定程度上与AH遗传加重因素有关。
