Dzizinskiĭ A A, Kalmykov S V
Ter Arkh. 1991;63(4):73-6.
A study was made of the luminol-dependent leukocyte chemiluminescence (LCL) of the whole blood in 45 patients with acute myocardial infarction (AMI). It has been shown that measurement of LCL during the first examination of the patient may play a significant part in the diagnosis of AMI. LCL monitoring is of independent importance for the control of resorption and reparative processes and for the diagnosis of the lingering course and threatened relapse of AMI. The authors provide evidence for the concept of the trigger inclusion of the leukocytic component into the chain of pathophysiological processes in AMI at hours 5-10 since its onset. Derangement of that mechanism may be one of the causes of the lingering and recurrent course of infarction. The treatment of AMI should be carried out with regard to the effect of therapeutic modalities on leukocyte function as well as to the phase of the pathophysiological process.
对45例急性心肌梗死（AMI）患者全血的鲁米诺依赖性白细胞化学发光（LCL）进行了研究。结果表明，在患者首次检查时测量LCL对AMI的诊断可能具有重要意义。LCL监测对于控制吸收和修复过程以及诊断AMI的迁延病程和复发风险具有独立的重要性。作者提供证据支持这样的概念，即在AMI发病后5至10小时，白细胞成分被触发纳入病理生理过程链中。该机制紊乱可能是梗死迁延和复发病程的原因之一。AMI的治疗应考虑治疗方式对白细胞功能的影响以及病理生理过程的阶段。
