IVF Unit, Division of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.
Fertil Steril. 2011 Jan;95(1):64-7. doi: 10.1016/j.fertnstert.2010.06.064. Epub 2010 Aug 5.
To compare the results of in vitro maturation (IVM) of oocytes for fertility preservation performed during the luteal phase of the cycle with those of IVM performed during the follicular phase.
Retrospective chart review (August 2007 to June 2009).
Academic tertiary referral fertility center.
PATIENT(S): Cancer patients who underwent treatment for fertility preservation.
INTERVENTION(S): IVM treatment during either luteal or follicular phase.
MAIN OUTCOME MEASURE(S): Number of oocytes, maturation and fertilization rates, and number of oocytes and embryos that were frozen.
RESULT(S): Eighteen cancer patients underwent IVM fertility preservation, five in their luteal phase and 13 in their follicular phase. The baseline characteristics of both groups were similar. There were no significant differences in the number of retrieved oocytes, maturation rates, fertilization rates, or the total number of oocytes and embryos that were cryopreserved.
CONCLUSION(S): These results suggest that IVM during the luteal phase can be offered to patients as an optional treatment for urgent fertility preservation when there is insufficient time for conventional follicular phase oocyte retrieval before chemotherapy must be initiated.
比较在黄体期进行的体外成熟（IVM）卵子用于生育保存的结果与在卵泡期进行的 IVM 的结果。
回顾性图表分析（2007 年 8 月至 2009 年 6 月）。
学术三级转诊生育中心。
接受治疗以保存生育能力的癌症患者。
黄体期或卵泡期进行 IVM 治疗。
卵母细胞数量、成熟和受精率，以及冷冻的卵母细胞和胚胎数量。
18 名癌症患者接受了 IVM 生育保存，5 名在黄体期，13 名在卵泡期。两组的基线特征相似。在取回的卵母细胞数量、成熟率、受精率或冷冻的卵母细胞和胚胎总数方面，均无显著差异。
这些结果表明，当在开始化疗之前没有足够的时间进行常规卵泡期卵母细胞取出时，黄体期的 IVM 可以作为紧急生育保存的一种选择治疗方法提供给患者。
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