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The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD).

作者信息

Valent Peter, Arock Michel, Akin Cem, Sperr Wolfgang R, Reiter Andreas, Sotlar Karl, Hartmann Karin, George Tracy I, Brockow Knut, Kluin-Nelemans Hanneke C, Gotlib Jason, Metcalfe Dean D, Horny Hans-Peter

出版信息

Blood. 2010 Aug 5;116(5):850-1. doi: 10.1182/blood-2010-05-285270.

DOI:10.1182/blood-2010-05-285270
PMID:20688965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2918335/
Abstract
摘要

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1
The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD).系统性肥大细胞增多症的分类应包括肥大细胞白血病(MCL)和伴有克隆性血液学非肥大细胞谱系疾病的系统性肥大细胞增多症(SM-AHNMD)。
Blood. 2010 Aug 5;116(5):850-1. doi: 10.1182/blood-2010-05-285270.
2
Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components.伴有克隆性血液非肥大细胞系疾病的系统性肥大细胞增生症:SM 和 AHNMD 成分中染色体异常的临床意义和比较。
Am J Hematol. 2013 Mar;88(3):219-24. doi: 10.1002/ajh.23380.
3
Proposal for a revised classification of systemic mastocytosis.关于系统性肥大细胞增多症修订分类的提议。
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4
Diagnostic criteria and classification of mastocytosis: a consensus proposal.肥大细胞增多症的诊断标准与分类:一项共识提议。
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5
Systemic mastocytosis: progressive evolution of an occult disease into fatal mast cell leukemia: unique findings on an unusual hematological neoplasm.系统性肥大细胞增生症:隐匿性疾病向致命性肥大细胞白血病的进展:一种不常见血液肿瘤的独特表现。
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Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations.系统性肥大细胞增多症伴相关克隆性血液系统非肥大细胞谱系疾病:临床病理特征及活化型c-kit突变分析
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Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management.成人系统性肥大细胞增生症:诊断、危险分层和治疗的 2012 年更新。
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Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations KITD816V and JAK2V617F.与慢性特发性骨髓纤维化相关的系统性肥大细胞增多症:系统性肥大细胞增多症的一种独特亚型,与一种携带激活点突变KIT D816V和JAK2 V617F的克隆性血液非肥大细胞谱系疾病相关。 (注:原文中“[corrected]”表示此处可能是修正后的内容,翻译时保留原样。)
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Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD).与系统性肥大细胞增多症(SM-AHNMD)相关的克隆性血液非肥大细胞谱系疾病中 KITD816V 的可变存在。
J Pathol. 2010 Apr;220(5):586-95. doi: 10.1002/path.2677.

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Indian J Hematol Blood Transfus. 2019 Jan;35(1):3-11. doi: 10.1007/s12288-019-01084-y. Epub 2019 Jan 24.
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Serum total tryptase level confirms itself as a more reliable marker of mast cells burden in mast cell leukaemia (aleukaemic variant).血清总类胰蛋白酶水平证实自身是肥大细胞白血病(无白血病变异型)中肥大细胞负荷更可靠的标志物。
Case Rep Hematol. 2015;2015:737302. doi: 10.1155/2015/737302. Epub 2015 Feb 10.
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Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.非典型慢性粒细胞白血病、慢性粒单核细胞白血病及无法分类的骨髓增生异常综合征/骨髓增殖性肿瘤的分子发病机制
Int J Hematol. 2015 Mar;101(3):229-42. doi: 10.1007/s12185-014-1670-3. Epub 2014 Sep 12.
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Advanced systemic mastocytosis: the impact of KIT mutations in diagnosis, treatment, and progression.高级系统性肥大细胞增生症:KIT 突变对诊断、治疗和进展的影响。
Eur J Haematol. 2013 Feb;90(2):89-98. doi: 10.1111/ejh.12043.

本文引用的文献

1
Differential diagnoses of systemic mastocytosis in routinely processed bone marrow biopsy specimens: a review.系统性肥大细胞增多症在常规处理的骨髓活检标本中的鉴别诊断:综述。
Pathobiology. 2010;77(4):169-80. doi: 10.1159/000305552. Epub 2010 Jul 7.
2
Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms.伴有全身肥大细胞活化症状的克隆性肥大细胞疾病的临床、生物学和分子特征。
J Allergy Clin Immunol. 2010 Jun;125(6):1269-1278.e2. doi: 10.1016/j.jaci.2010.02.019.
3
Proposal for a revised classification of systemic mastocytosis.关于系统性肥大细胞增多症修订分类的提议。
Blood. 2010 Apr 1;115(13):2720-1. doi: 10.1182/blood-2009-12-259085.
4
Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD).与系统性肥大细胞增多症(SM-AHNMD)相关的克隆性血液非肥大细胞谱系疾病中 KITD816V 的可变存在。
J Pathol. 2010 Apr;220(5):586-95. doi: 10.1002/path.2677.
5
Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis.在一部分“特发性”过敏反应患者中,发现具有克隆标记的异常肥大细胞群体。
Blood. 2007 Oct 1;110(7):2331-3. doi: 10.1182/blood-2006-06-028100. Epub 2007 Jul 16.
6
Mastocytosis: state of the art.肥大细胞增多症:最新进展
Pathobiology. 2007;74(2):121-32. doi: 10.1159/000101711.
7
Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria.肥大细胞增多症的标准与标准化:关于诊断、治疗建议及反应标准的共识声明
Eur J Clin Invest. 2007 Jun;37(6):435-53. doi: 10.1111/j.1365-2362.2007.01807.x.
8
Diagnostic criteria and classification of mastocytosis: a consensus proposal.肥大细胞增多症的诊断标准与分类:一项共识提议。
Leuk Res. 2001 Jul;25(7):603-25. doi: 10.1016/s0145-2126(01)00038-8.