Chaudhary S C, Kumar Vivek, Gupta Abhinav
Department of Medicine, CSM Medical University, Lucknow, UP, India.
Trop Doct. 2010 Oct;40(4):238-9. doi: 10.1258/td.2010.100049. Epub 2010 Aug 5.
Malaria is a common health problem in India and contributes about 80% of the total cases in South East Asia. Falciparum malaria is known for its various complications, including cerebral malaria, severe anaemia, acute renal failure, acute lung injury, jaundice (and hepatic involvement), hypoglycaemia and circulatory collapse. We hereby report on a young male who was suffering from complicated falciparum malaria, and had purpura fulminans along with laboratory features suggestive of disseminated intravascular coagulation. He was treated with intravenous (IV) artesunate, low molecular weight heparin followed by warfarin in addition to IV fluids to which he showed gradual response. We have presented this case to make others vigilant enough to suspect malaria in differential diagnosis of purpura fulminans.
疟疾是印度常见的健康问题，约占东南亚疟疾病例总数的80%。恶性疟以其各种并发症而闻名，包括脑型疟疾、严重贫血、急性肾衰竭、急性肺损伤、黄疸（及肝脏受累）、低血糖和循环衰竭。我们在此报告一名患有复杂恶性疟的年轻男性，他出现了暴发性紫癜以及提示弥散性血管内凝血的实验室特征。除静脉补液外，他接受了静脉注射青蒿琥酯、低分子量肝素治疗，随后使用华法林，病情逐渐好转。我们展示此病例是为了让其他人在暴发性紫癜的鉴别诊断中足够警惕，怀疑疟疾。
