Farkouh Christopher S, Abdi Parsa, Amatul-Hadi Faiza, Anthony Michelle R, Ali Khan Qaisar, Manja Kyla, Manja Christian, Ali Syed Masood
Dermatology, Rush Medical College, Chicago, USA.
Faculty of Medicine, Memorial University of Newfoundland, St. John's, CAN.
Cureus. 2023 Jul 11;15(7):e41706. doi: 10.7759/cureus.41706. eCollection 2023 Jul.
Malaria is a vector-borne tropical infection caused by protozoa of the genus and is transmitted by the bite of an infected Anopheles mosquito. The disease is commonly characterized by fever, edema, thrombocytopenia, hypoglycemia, anemia, and myalgias; however, the infection's cutaneous presentations are not commonly emphasized and tend to be overlooked. A literature search was conducted that focused on the various skin pathologies that malaria patients have been noted to present with using case reports and currently available literature. We describe the various skin manifestations associated with malaria, such as purpura fulminans, febrile urticaria, cutaneous leishmaniasis co-infections, urticaria infectiosum, vivax-induced severe thrombocytopenia petechiae, acral skin necrosis, and reticulated erythema, and how each of these skin manifestations may provide insight into the patient's prognosis. Documentation and vigilance regarding these cutaneous manifestations must be emphasized as they may lead to better patient outcomes and a stronger understanding of the patient's underlying malaria.
疟疾是一种由疟原虫属原生动物引起的媒介传播热带感染病，通过受感染的按蚊叮咬传播。该疾病通常的特征为发热、水肿、血小板减少、低血糖、贫血和肌痛；然而，感染的皮肤表现通常未得到重视且往往被忽视。我们通过病例报告和现有文献进行了一项文献检索，重点关注疟疾患者出现的各种皮肤病变。我们描述了与疟疾相关的各种皮肤表现，如暴发性紫癜、热性荨麻疹、皮肤利什曼病合并感染、传染性荨麻疹、间日疟诱发的严重血小板减少性瘀点、肢端皮肤坏死和网状红斑，以及这些皮肤表现中的每一种如何为患者的预后提供线索。必须强调对这些皮肤表现的记录和警惕，因为它们可能带来更好的患者治疗效果，并加深对患者潜在疟疾的了解。
