Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Dement Geriatr Cogn Disord. 2010;30(1):39-42. doi: 10.1159/000315509. Epub 2010 Jul 31.
Some studies have suggested a lower incidence of cancer in patients with dementia. We studied this further for 18 cancer types in population-based registers.
In 19,756 cases and in 147,324 age- and sex-matched controls a diagnosis of dementia was studied 9-45 months prior to the diagnosis of cancer.
Overall a diagnosis of dementia was significantly less common among the cancer cases (risk ratio, RR = 0.60; 95% CI = 0.52-0.69).
The study confirms previous findings that patients with dementia have a lower risk of cancer. Because the effect was seen for all tumour types and especially for patients older than 70 years and since the deficit was more pronounced for patients with tumours situated within the body, the data suggest that malignancies are underdiagnosed for persons with dementia.
一些研究表明，痴呆症患者的癌症发病率较低。我们在基于人群的登记处针对 18 种癌症类型进一步对此进行了研究。
在 19756 例病例和 147324 名年龄和性别匹配的对照中，在癌症诊断前 9-45 个月研究了痴呆症的诊断。
总体而言，痴呆症的诊断在癌症病例中明显较少（风险比，RR = 0.60；95%置信区间，CI = 0.52-0.69）。
该研究证实了先前的发现，即痴呆症患者的癌症风险较低。由于该效应见于所有肿瘤类型，尤其是 70 岁以上的患者，并且由于身体内部肿瘤的患者的缺陷更为明显，因此数据表明，痴呆症患者的恶性肿瘤漏诊率较高。
