Mucosa-associated lymphoma tissue of the dura presenting as meningioma.

Mucosa-associated lymphoma tissue (MALT) of the dura is extremely rare, with only a few reported cases worldwide. We present a unique case of a 61-year-old female who presented with neurologic symptoms of unsteady gait, dizziness, and sharp pain on her scalp for 3 weeks. A subsequent magnetic resonance imaging (MRI) of the brain demonstrated a dural-based mass radiographically consistent with meningioma. However, biopsy revealed the cells to be immunopositive for CD20 and CD79a, and immunonegative for CD5, CD10, CD43, and CD23. The neoplastic small lymphoid B cells were MUM1 positive and showed kappa light chain restriction, consistent with MALT of the dura. No evidence of systemic disease was found. The patient underwent radiation, which resulted in a complete response. MALT lymphoma, while rare, must be considered in the differential diagnosis in patients presenting radiographically with meningioma.