Li J-B, Asakawa A, Li Y, Cheng K, Inui A
Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
Exp Clin Endocrinol Diabetes. 2011 Mar;119(3):163-6. doi: 10.1055/s-0030-1262790. Epub 2010 Aug 5.
Ghrelin and peptide YY (PYY) are brain-gut peptides that have a variety of physiological functions and are involved in energy regulation. Thus far, abnormalities in the expression and secretion of ghrelin and PYY are known to occur in lifestyle-related diseases, including obesity, and the improvement of these abnormalities has become an important challenge. Exercise has recently been reported to influence ghrelin and PYY concentrations. Exercise increases the PYY secretion. The effects of exercise on ghrelin levels vary with the study subject, timing of exercise, and duration of exercise. Here, we review the findings of recent studies on the association of PYY and ghrelin with obesity, particularly, on the influence of exercise on PYY and ghrelin levels.
胃饥饿素和肽YY（PYY）是脑肠肽，具有多种生理功能并参与能量调节。迄今为止，已知在包括肥胖症在内的生活方式相关疾病中会出现胃饥饿素和PYY表达及分泌异常，改善这些异常已成为一项重大挑战。最近有报道称运动可影响胃饥饿素和PYY的浓度。运动可增加PYY的分泌。运动对胃饥饿素水平的影响因研究对象、运动时间和运动持续时间而异。在此，我们综述了近期关于PYY和胃饥饿素与肥胖症关联的研究结果，特别是运动对PYY和胃饥饿素水平的影响。
