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分娩急性期反应:津巴布韦的一项横断面研究。

The acute phase response to parturition: a cross-sectional study in Zimbabwe.

作者信息

Friis Henrik, Gomo Exnevia, Mashange Wilson, Nyazema Norman, Kostel Pernille, Wieringa Frank, Krarup Henrik

机构信息

Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Rolighedsvej 30, 1958 Frederiksberg, Denmark.

出版信息

Afr J Reprod Health. 2009 Jun;13(2):61-8.

PMID:20690249
Abstract

Parturition triggers an acute phase response, but its magnitude, duration and predictors are not well described. We determined serum alpha1-antichymotrypsin (ACT) and C-reactive protein (CRP) among 216 women attending postpartum services in south-eastern Zimbabwe. Serum CRP peaked during the first week and serum ACT around 9 days postpartum. Serum ACT, but not serum CRP, was lower among HIV infected women. Multiparity was a negative, and preterm delivery and caesarean section were positive predictors of both serum ACT and CRP. There is a need for a better understanding of the acute phase response to parturition.

摘要

分娩会引发急性期反应,但其程度、持续时间和预测因素尚无详尽描述。我们测定了津巴布韦东南部216名接受产后服务的妇女的血清α1-抗糜蛋白酶(ACT)和C反应蛋白(CRP)。血清CRP在第一周达到峰值,血清ACT在产后约9天达到峰值。HIV感染女性的血清ACT较低,但血清CRP无此情况。多胎妊娠是血清ACT和CRP的负向预测因素,早产和剖宫产是血清ACT和CRP的正向预测因素。有必要更好地了解分娩后的急性期反应。

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