Pisarik Paul
Family Medicine, University of Oklahoma, School of Community Medicine, Tulsa, OK 74120-5440, USA.
J Prim Health Care. 2010 Mar;2(1):22-8.
Asthma affects around 5% of the United States population, with 50% having uncontrolled symptoms.
To improve asthma care by seeing if the inhaled corticosteroid to bronchodilator ratio (RATIO) is associated with asthma control and if non-clinical factors were associated with adherence to asthma guidelines.
A retrospective study using University of Oklahoma-Tulsa, School of Community Medicine Family Medicine Clinic electronic medical records of a random sample of 49 patients with asthma who were seen at least twice from July 2003 through June 2007 and did not have a diagnosis of chronic obstructive pulmonary disease or exercise-induced asthma.
The RATIO for those prescribed corticosteroid inhalers was directly related to the actual step of asthma care (STEP) but inversely related to the number of prednisone courses prescribed per year (R2 =.30, p = 0.0012). The difference between the actual STEP and ideal STEP (had corticosteroid inhalers been prescribed for all the months in the study) was directly related to the percent of available salbutamol (albuterol) inhalersthat non-clinicians refilled and inversely related to the actual STEP (R2 = .45, p = 1.8 x 10(-5)). The available corticosteroid inhalers prescribed was directly related to the actual STEP and inversely related to the number of comorbid diagnoses addressed at the last asthma visit (R2 = .70, p = 5.8 x 10(-10)).
Efforts to both limit salbutamol medications, especially by non-clinicians, and simultaneously prescribe appropriate amounts of inhaled corticosteroids, through a dedicated asthma visit, should improve asthma control. A higher RATIO implies better asthma control.
哮喘影响着约5%的美国人口,其中50%的人症状未得到控制。
通过研究吸入性糖皮质激素与支气管扩张剂的比例(RATIO)是否与哮喘控制相关,以及非临床因素是否与哮喘指南的依从性相关,来改善哮喘护理。
一项回顾性研究,使用俄克拉荷马大学塔尔萨分校社区医学与家庭医学学院诊所的电子病历,随机抽取了49例哮喘患者,这些患者在2003年7月至2007年6月期间至少就诊两次,且未被诊断为慢性阻塞性肺疾病或运动诱发性哮喘。
使用糖皮质激素吸入器患者的RATIO与哮喘护理的实际步骤(STEP)直接相关,但与每年开具的泼尼松疗程数呈负相关(R2 = 0.30,p = 0.0012)。实际STEP与理想STEP(如果在研究的所有月份都开具糖皮质激素吸入器)之间的差异与非临床医生补充的可用沙丁胺醇(舒喘灵)吸入器的百分比直接相关,与实际STEP呈负相关(R2 = 0.45,p = 1.8×10⁻⁵)。开具的可用糖皮质激素吸入器与实际STEP直接相关,与上次哮喘就诊时处理的合并诊断数量呈负相关(R2 = 0.70,p = 5.8×10⁻¹⁰)。
通过专门的哮喘就诊,限制沙丁胺醇药物的使用,尤其是非临床医生的使用,并同时开具适量的吸入性糖皮质激素,应能改善哮喘控制。较高的RATIO意味着更好的哮喘控制。