双金属镍铝介导的吡啶对位选择性烯基化反应：在 C-H 键活化之前直接观察到 η2,η1-吡啶 Ni(0)-Al(III)中间体。

Bimetallic nickel aluminum mediated para-selective alkenylation of pyridine: direct observation of eta2,eta1-pyridine Ni(0)-Al(III) intermediates prior to C-H bond activation.

机构信息

Institute of Chemistry, Academia Sinica, Nangang, Taipei, Taiwan, Republic of China.

出版信息

J Am Chem Soc. 2010 Sep 1;132(34):11887-9. doi: 10.1021/ja1061246.

PMID:20690626

Abstract

We have presented new amino-NHC Ni-Al complex mediated para C-H bond activation for pyridine and quinolin, and isolated for the first time the intermediate structure of a bimetallic eta(2),eta(1)-pyridine nickel aluminum complex prior to its C-H activation, which serves as key evidence for bimetallic catalysis.

摘要

我们提出了一种新型的氨基-NHC Ni-Al 配合物介导的吡啶和喹啉的对位 C-H 键活化，并首次分离得到了双金属 η(2),η(1)-吡啶镍铝配合物在其 C-H 活化之前的中间体结构，这为双金属催化提供了关键证据。