Fouché C, Ramos A, Esperandieu O, Briault S, Martin J-G, Desroches A
Pôle mère-enfant, service gynécologie-obstétrique, centre hospitalier régional d'Orléans, BP 2439, 45032 Orléans cedex 1, France.
J Gynecol Obstet Biol Reprod (Paris). 2010 Dec;39(8):667-71. doi: 10.1016/j.jgyn.2010.06.002. Epub 2010 Aug 6.
Risk for leukemic conditions increases in individuals with Down syndrome. We report a third trimester antenatal diagnosis of leukemia in a Down syndrome fetus. The third trimester ultrasound examination revealed a hepatosplenomegaly, which may suggest a myelopoiesis disorder. A review of the literature of eight cases described antenatally and 14 cases in the immediate neonatal period is presented.
唐氏综合征患者患白血病的风险会增加。我们报告了一例唐氏综合征胎儿在孕晚期的产前白血病诊断。孕晚期超声检查显示肝脾肿大，这可能提示骨髓造血障碍。本文综述了8例产前描述病例和14例新生儿期病例的文献。
