Silliman C C, Ford D M, Lane P A
Department of Pediatrics, University of Colorado School of Medicine, Denver 80262.
Am J Pediatr Hematol Oncol. 1991 Summer;13(2):176-8. doi: 10.1097/00043426-199122000-00014.
A 5-year-old child with hemolytic uremic syndrome developed bleeding due to vitamin K deficiency 9 days after the onset of a diarrheal prodrome. Vitamin K deficiency was documented by rapid correction of the PT and PTT and cessation of bleeding following administration of vitamin K, as well as by the detection of noncarboxylated prothrombin in plasma. The case is instructive because it suggests that previously healthy older children who become acutely ill may develop vitamin K deficiency more rapidly than heretofore has been appreciated.
一名5岁溶血尿毒综合征患儿在腹泻前驱症状出现9天后因维生素K缺乏而发生出血。通过凝血酶原时间（PT）和部分凝血活酶时间（PTT）的迅速纠正以及维生素K给药后出血停止，以及血浆中未羧化凝血酶原的检测，证实了维生素K缺乏。该病例具有指导意义，因为它表明以前健康的大龄儿童在急性发病时可能比以往认识到的更迅速地发生维生素K缺乏。
