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角膜基质环段治疗圆锥角膜的散光修正与改良。

Modification and refinement of astigmatism in keratoconic eyes with intrastromal corneal ring segments.

机构信息

Keratoconus Unit, Vissum Corporation, and Departamento de Optica, Farmacología y Anatomía, Universidad de Alicante, Alicanted, Spain.

出版信息

J Cataract Refract Surg. 2010 Sep;36(9):1562-72. doi: 10.1016/j.jcrs.2010.04.029.

DOI:10.1016/j.jcrs.2010.04.029
PMID:20692571
Abstract

PURPOSE

To analyze corneal astigmatic changes after implantation of intrastromal corneal ring segments (ICRS) in keratoconic eyes using the Alpins vectorial method.

SETTING

Vissum Corporation, Alicante, Spain.

METHODS

Keraring ICRS were implanted in eyes with a diagnosis of keratoconus. One of 3 surgeons performed the ICRS implantations using femtosecond technology and following the same protocol. Visual, refractive, keratometric, and corneal aberrometric changes were evaluated during a 12-month follow-up. Corneal astigmatic changes were also analyzed using the following Alpins vectorial components: targeted induced astigmatism (TIA), surgically induced astigmatism (SIA), difference vector, magnitude of error, flattening effect, and torque.

RESULTS

Postoperatively, there was significant visual improvement (P = .03), significant central flattening (P = .03), and a significant reduction in manifest astigmatism (P<.01). The magnitude of SIA vector was significantly lower than the TIA postoperatively (P>or=.02). The mean magnitude of the difference vector 3 months postoperatively was +2.96 diopters (D) +/- 1.68 (SD). The mean magnitude of error remained negative and unchanged (P>or=.10). The mean magnitude of the flattening effect was significantly lower than the TIA at all postoperative visits (P<or=.01). The mean magnitude of torque vector was 1.21 +/- 0.98 D at 3 months. Significant negative correlations were found between preoperative corneal astigmatism and the magnitude of error and difference vector at all postoperative visits.

CONCLUSION

Although ICRS implantation significantly reduced the magnitude of corneal astigmatism, there was a trend toward undercorrection and the meridian of correction was not appropriate in all cases, showing the need for nomogram adjustments.

摘要

目的

使用 Alpins 向量分析方法分析圆锥角膜患者行角膜基质内环植入术后的角膜散光变化。

设置

西班牙阿利坎特的 Vissum 公司。

方法

对诊断为圆锥角膜的患者眼行 Keraring ICRS 植入术。3 位医生中的 1 位医生采用飞秒技术并遵循相同的方案进行 ICRS 植入。在 12 个月的随访期间评估视力、屈光、角膜曲率和角膜像差的变化。采用以下 Alpins 向量成分分析角膜散光变化:目标诱导散光(TIA)、手术诱导散光(SIA)、差异向量、误差幅度、变平效应和扭矩。

结果

术后视力明显提高(P =.03),中央角膜明显变平(P =.03),角膜散光明显减少(P<.01)。术后 SIA 向量幅度明显低于 TIA(P>.02)。术后 3 个月差异向量的平均幅度为+2.96 屈光度(D) +/- 1.68(SD)。误差幅度的平均值仍为负值且不变(P>.10)。术后所有随访时的变平效应平均幅度均明显低于 TIA(P<.01)。术后 3 个月扭矩向量的平均幅度为 1.21 +/- 0.98 D。术前角膜散光与术后所有随访时的误差幅度和差异向量之间均存在显著负相关。

结论

尽管 ICRS 植入术可显著降低角膜散光的幅度,但存在欠矫趋势,且在所有情况下矫正子午线均不合适,表明需要调整列线图。

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