Ding Jian, Qi Lin, Zu Xiongbing, Shen Pengfei
Department of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Jul;35(7):705-10. doi: 10.3969/j.issn.1672-7347.2010.07.010.
To evaluate urinary dynamics in the diagnosis, differential diagnosis, disease grades, complications, prognosis, and curative effect on benign prostatic hyperplasia (BPH) patients accompanied with diabetic mellitus (DM), and to investigate the clinical significance of urodynamic studies.
A total of 106 BPH patients with lower urinary tract symptoms were studied, aged 53-92(63.21+/-7.18) years. The mean duration of voiding symptoms was 3-12 years. These patients were divided into 2 groups: Group A consisted of 59 BPH patients while Group B consisted of 47 BPH patients combined with DM. Both groups were evaluated the international prostate symptom score(IPSS), urine flow rate, and residual urine volume. All patients underwent urodynamic examination. Correlation analysis was conducted to determine the correlation among the patients. The urodynamic results in different groups were compared.
The IPSS in Group A was higher than Group B, while the Qmax was lower than Group B. The unsatisfactory results of Group A was higher than Group B. There was significant difference between the 2 groups (P<0.05). There was no significant difference in residual urine volume between the 2 groups (P>0. 05). There was significant difference between the 2 groups in detrusor instability of the bladder, low compliance bladder, and damaged detrusor function (P<0.05).
The influence of DM on the function of the bladder in BPH patients is significant. Urodynamics can provide objective basis for the selection of therapeutic methods, and forecast the postoperative effect. It has an important reference value in BPH patients accompanied with DM.
评估尿动力学在伴糖尿病(DM)的良性前列腺增生(BPH)患者的诊断、鉴别诊断、疾病分级、并发症、预后及疗效中的应用,并探讨尿动力学检查的临床意义。
对106例有下尿路症状的BPH患者进行研究,年龄53 - 92(63.21±7.18)岁。排尿症状平均持续时间为3 - 12年。这些患者分为2组:A组为59例BPH患者,B组为47例合并DM的BPH患者。两组均评估国际前列腺症状评分(IPSS)、尿流率及残余尿量。所有患者均接受尿动力学检查。进行相关性分析以确定患者之间的相关性。比较不同组的尿动力学结果。
A组的IPSS高于B组,而最大尿流率(Qmax)低于B组。A组不满意结果高于B组。两组间差异有统计学意义(P<0.05)。两组残余尿量差异无统计学意义(P>0.05)。两组在膀胱逼尿肌不稳定、膀胱顺应性降低及逼尿肌功能受损方面差异有统计学意义(P<0.05)。
DM对BPH患者膀胱功能的影响显著。尿动力学可为治疗方法的选择提供客观依据,并预测术后效果。其在伴DM的BPH患者中有重要参考价值。