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糖尿病患者的膀胱过度活动症:一项基于问卷的观察性调查。

Overactive bladder in diabetes mellitus patients: a questionnaire-based observational investigation.

作者信息

Palleschi Giovanni, Pastore Antonio Luigi, Maggioni Cristina, Fuschi Andrea, Pacini Luca, Petrozza Vincenzo, Carbone Antonio

机构信息

Unit of Urology ICOT, Department of Medical and Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine, Sapienza University of Rome, Corso della Repubblica 79, 04100, Latina, LT, Italy.

出版信息

World J Urol. 2014 Aug;32(4):1021-5. doi: 10.1007/s00345-013-1175-3. Epub 2013 Oct 8.

DOI:10.1007/s00345-013-1175-3
PMID:24100404
Abstract

PURPOSE

Bladder dysfunction, secondary to diabetes, is mainly characterized by poor bladder emptying and overflow incontinence. However, there is evidence in literature that storage symptoms, as those suggestive for overactive bladder (OAB), may also affect people with diabetes. The aim of this study was to evaluate the prevalence of overactive bladder, the complaint of urinary urgency with/without urge incontinence, usually with frequency and nocturia, in people with diabetes compared to healthy subjects (control group).

METHODS

Symptoms were assessed through the overactive bladder questionnaire (OAB-q), an investigative tool, specifically developed for OAB diagnosis.

RESULTS

OAB-q scores resulted higher in diabetic people than those of the control group. Age and disease duration resulted in measurements that showed a statistical correlation with the OAB-q scores.

CONCLUSIONS

OAB symptoms are more prevalent in diabetic people than in non-diabetic people. This prompts further research to determine whether the onset of OAB symptoms can be considered as an indicator of diabetic neuropathy.

摘要

目的

继发于糖尿病的膀胱功能障碍主要表现为膀胱排空不良和充溢性尿失禁。然而,文献中有证据表明,诸如提示膀胱过度活动症(OAB)的储尿期症状也可能影响糖尿病患者。本研究的目的是评估与健康受试者(对照组)相比,糖尿病患者中膀胱过度活动症(即伴有/不伴有急迫性尿失禁的尿急主诉,通常伴有尿频和夜尿症)的患病率。

方法

通过膀胱过度活动症问卷(OAB-q)评估症状,该问卷是专门为OAB诊断开发的一种调查工具。

结果

糖尿病患者的OAB-q评分高于对照组。年龄和病程的测量结果显示与OAB-q评分存在统计学相关性。

结论

OAB症状在糖尿病患者中比非糖尿病患者更普遍。这促使进一步研究以确定OAB症状的出现是否可被视为糖尿病神经病变的一个指标。

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Taiwan J Obstet Gynecol. 2012 Sep;51(3):381-6. doi: 10.1016/j.tjog.2012.07.011.
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The epidemiology of urinary incontinence in women with type 2 diabetes.女性 2 型糖尿病患者尿失禁的流行病学。
J Urol. 2012 Nov;188(5):1816-21. doi: 10.1016/j.juro.2012.07.027. Epub 2012 Sep 19.
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Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes.
袖状胃切除术对肥胖女性患者盆底功能障碍的影响:一项前瞻性研究。
Obes Surg. 2023 Oct;33(10):3069-3076. doi: 10.1007/s11695-023-06725-w. Epub 2023 Jul 10.
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Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction.氧化应激在糖尿病膀胱功能障碍发病机制中的潜在作用。
Nat Rev Urol. 2022 Oct;19(10):581-596. doi: 10.1038/s41585-022-00621-1. Epub 2022 Aug 16.
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Excitability and contractility in arterioles and venules from the urinary bladder.来自膀胱的小动脉和小静脉的兴奋性和收缩性。
Curr Top Membr. 2020;85:301-326. doi: 10.1016/bs.ctm.2020.01.003. Epub 2020 Feb 17.
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Macrovascular Complications and Prevalence of Urgency Incontinence in Japanese Patients with Type 2 Diabetes Mellitus: The Dogo Study.日本2型糖尿病患者的大血管并发症与急迫性尿失禁患病率:道后研究
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