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空气污染对成人肺功能的影响。

Effects of air pollution on adult pulmonary function.

作者信息

Xu X P, Dockery D W, Wang L H

机构信息

School of Public Health, Harvard University, Boston, Massachusetts.

出版信息

Arch Environ Health. 1991 Jul-Aug;46(4):198-206. doi: 10.1080/00039896.1991.9937448.

DOI:10.1080/00039896.1991.9937448
PMID:2069427
Abstract

We conducted a study in three representative areas of Beijing to determine respiratory health effects of indoor and outdoor air pollution. In August 1986, we measured the lung function of 1,440 adults who were 40-69 y of age and who had never smoked. Forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1.0) were adjusted for height, sex, and age. Outdoor ambient air pollution measurements from the World Health Organization Global Air Pollution Monitoring Station were very different in the three study areas; the annual mean concentrations of sulfur dioxide (SO2) in residential, suburban, and industrial areas were 128, 18, and 57 micrograms/m3, respectively, and annual mean concentrations of total suspended particulate matter (TSPM) were 389, 261, and 449 micrograms/m3, respectively. Coal was most frequently used for domestic heating in the residential (92%) and suburban (96%) areas compared with the industrial area (17%). Heating with coal was associated with a reduced FEV1.0 (-91 +/- 36 ml) and FVC (-84 +/- 41 ml). Living in the residential area was associated with an additional reduction in FEV1.0 (-69 +/- 34 ml) and FVC (-257 +/- 37 ml). After we adjusted for age, height, and sex, an inverse linear association was found between In outdoor SO2 (or TSPM) concentration and FEV1.0 and FVC in subjects who had and had not used coal stove heating. Regression analysis results showed that a per-unit increase in In SO2 (TSPM) concentration (microgram/m3) could result in a 35.6 (131.4) ml reduction in FEV1.0 and a 142.2 (478.7) ml reduction in FVC.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们在北京三个具有代表性的地区开展了一项研究,以确定室内和室外空气污染对呼吸系统健康的影响。1986年8月,我们对1440名年龄在40至69岁之间且从未吸烟的成年人进行了肺功能测量。对用力肺活量(FVC)和1秒用力呼气量(FEV1.0)进行了身高、性别和年龄的校正。来自世界卫生组织全球空气污染监测站的室外环境空气污染测量结果在三个研究区域差异很大;居民区、郊区和工业区的二氧化硫(SO2)年均浓度分别为128、18和57微克/立方米,总悬浮颗粒物(TSPM)年均浓度分别为389、261和449微克/立方米。与工业区(17%)相比,居民区(92%)和郊区(96%)最常使用煤炭进行家庭取暖。用煤取暖与FEV1.0(-91±36毫升)和FVC(-84±41毫升)降低有关。居住在居民区与FEV1.0(-69±34毫升)和FVC(-257±37毫升)的额外降低有关。在对年龄、身高和性别进行校正后,发现无论是否使用煤炉取暖,受试者的室外SO2(或TSPM)浓度与FEV1.0和FVC之间存在负线性关联。回归分析结果表明,SO2(TSPM)浓度每增加一个单位(微克/立方米),FEV1.0可降低35.6(131.4)毫升,FVC可降低142.2(478.7)毫升。(摘要截断于250字)

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