Evidence-Based Medicine, Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
J Clin Hypertens (Greenwich). 2010 Aug;12(8):603-12. doi: 10.1111/j.1751-7176.2010.00311.x.
Chart reviews were conducted at 28 US physician practices to evaluate blood pressure (BP) management. The cross-sectional study included 8250 adult patients diagnosed with hypertension. The primary outcome variable was BP control (BP <140/90 mm Hg for nondiabetic and <130/80 mm Hg for diabetic patients). Mean body mass index was 30.9 kg/m(2), 49% were obese, 54% were women, mean age was 64.9 years, and 25% had diabetes. Mean BP was 132.2/77.8 mm Hg, and 55.8% of study participants had controlled BP. Patients with uncontrolled BP were more likely to be obese or African American, and more than twice as likely to have diabetes. Almost 1 in 5 nondiabetic patients (18%), and 38% of diabetic patients, were above goal BP by >10 mm Hg systolic or >5 mm Hg diastolic; among these patients, 36% used 0 or 1 antihypertensive medication, and 32% used 2 medications. Opportunity exists to improve BP control in this population.
在美国 28 家医生诊所进行了病历回顾,以评估血压(BP)管理情况。这项横断面研究纳入了 8250 名被诊断患有高血压的成年患者。主要结局变量是 BP 控制情况(非糖尿病患者的 BP<140/90mmHg,糖尿病患者的 BP<130/80mmHg)。平均体重指数为 30.9kg/m(2),49%的患者肥胖,54%为女性,平均年龄为 64.9 岁,25%的患者患有糖尿病。平均 BP 为 132.2/77.8mmHg,研究参与者中有 55.8%的人 BP 得到了控制。BP 控制不佳的患者更有可能肥胖或为非裔美国人,且患有糖尿病的可能性是前者的两倍多。近五分之一(18%)的非糖尿病患者和 38%的糖尿病患者的收缩压超过目标值>10mmHg 或舒张压超过目标值>5mmHg;在这些患者中,36%的人使用 0 或 1 种降压药物,32%的人使用 2 种药物。在该人群中,改善 BP 控制的机会依然存在。