University Hospital A. Gemelli, Catholic University of the Sacred Heart, Department of Pediatrics, Division of Neonatology, Largo Agostino Gemelli 8, 00168 Rome, Italy.
Pediatrics. 2010 Sep;126(3):e651-6. doi: 10.1542/peds.2009-3005. Epub 2010 Aug 9.
The goal was to assess the feasibility of earlier weaning from the incubator for preterm infants.
This was a prospective, randomized study with preterm infants with birth weights of <1600 g who were admitted to a neonatal subintensive ward. Findings for 47 infants who were transferred from an incubator to an open crib at >1600 g (early transition group) were compared with those for 47 infants who were transferred from an incubator to an open crib at >1800 g (standard transition [ST] group). The primary outcome of the study was length of stay. Secondary outcomes were the number of infants returned to an incubator, the growth velocity in an open crib and during the first week at home, the proportions of breastfeeding at discharge and during the first week at home, and the hospital readmission rate.
The length of stay was significantly shorter in the early transition group than in the standard transition group (23.5 vs 33 days; P=.0002). No infants required transfer back to the incubator. Only 1 infant in the standard transition group was readmitted to the hospital during the first week after discharge. Growth velocities and individual amounts of breastfeeding were similar between the 2 groups.
In this study, weaning of moderately preterm infants from incubators to open cribs at 1600 g was safe and resulted in earlier discharge.
评估将早产儿更早地从孵化器中断奶的可行性。
这是一项前瞻性、随机研究，纳入了入住新生儿亚重症病房的体重<1600g 的早产儿。将体重>1600g 时从孵化器转移到开放式婴儿床（早期过渡组）的 47 名婴儿的发现与体重>1800g 时从孵化器转移到开放式婴儿床（标准过渡[ST]组）的 47 名婴儿的发现进行了比较。研究的主要结局是住院时间。次要结局包括返回孵化器的婴儿数量、开放式婴儿床和在家第一周的生长速度、出院时和在家第一周母乳喂养的比例，以及住院再次入院率。
早期过渡组的住院时间明显短于标准过渡组（23.5 天比 33 天；P=0.0002）。没有婴儿需要转回孵化器。只有 1 名标准过渡组的婴儿在出院后第一周内再次住院。两组的生长速度和母乳喂养的个体量相似。
在这项研究中，将体重适中的早产儿从孵化器断奶至 1600g 的开放式婴儿床是安全的，并导致更早出院。
