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极低出生体重早产儿从保温箱提前转移至保温床的效果。

Effects of an early transfer from incubator to a warming crib in very low birthweight preterm infants.

机构信息

Department of Paediatrics I, Neonatology, Paediatric Intensive Care and Paediatric Neurology, Universitätsmedizin Essen, University of Duisburg-Essen, North-Rhine Westphalia, 45122, Essen, Germany.

Department of Health and Nursing, Occupational Therapy, Ernst-Abbe-University of Applied Sciences, Jena, Germany.

出版信息

BMC Pediatr. 2024 May 9;24(1):319. doi: 10.1186/s12887-024-04795-y.

DOI:10.1186/s12887-024-04795-y
PMID:38724933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11080167/
Abstract

PURPOSE

Very low birth weight infants are cared for postnatally in the incubator because of adverse consequences of hypothermia. Data on the optimal weight of transfer to a warming crib are rare. The aim of this study was to determine the course of temperature and body weight during a standardized transfer to a warming crib at a set weight.

METHODS

Prospective intervention study in very low birthweight infants who were transferred from the incubator to a warming crib at a current weight between 1500 g and 1650 g.

RESULTS

No infant had to be transferred back to an incubator. Length of hospital stay was equal compared to a historical cohort from the two years directly before the intervention. The intervention group showed an increase in the volume fed orally on the day after transfer to the warming crib, although this did not translate into an earlier discontinuation of gavage feedings. Compared to the historical group, infants in the intervention group could be transferred to an unheated crib at an earlier postmenstrual age and weight.

CONCLUSIONS

Early transfer from the incubator to a warming crib between 1500 g and 1650 g is feasible and not associated with adverse short-term events or outcomes.

TRIAL REGISTRATION

DRKS-IDDRKS00031832.

摘要

目的

由于体温过低会带来不良后果,极低出生体重儿在出生后会被放在保温箱中进行护理。关于转移到保温婴儿床的最佳体重的数据很少。本研究的目的是确定在以设定体重转移到保温婴儿床的过程中体温和体重的变化。

方法

这是一项在极低出生体重儿中进行的前瞻性干预研究,这些婴儿在 1500-1650 克之间的当前体重时从保温箱转移到保温婴儿床。

结果

没有婴儿需要转回保温箱。与干预前两年的历史队列相比,住院时间相同。干预组在转移到保温婴儿床后的第二天,口服喂养量增加,尽管这并没有转化为更早地停止管饲喂养。与历史组相比,干预组的婴儿可以更早地在未加热的婴儿床中,以更接近胎龄和更重的体重进行转移。

结论

在 1500-1650 克之间从保温箱早期转移到保温婴儿床是可行的,不会导致短期不良事件或结局。

临床试验注册号

DRKS-IDDRKS00031832。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cf9/11080167/b073c833c7a5/12887_2024_4795_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cf9/11080167/b073c833c7a5/12887_2024_4795_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cf9/11080167/b073c833c7a5/12887_2024_4795_Fig1_HTML.jpg

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本文引用的文献

1
Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial.将中度早产儿从孵化器转入婴儿床:一项随机临床试验。
J Pediatr. 2019 Jan;204:96-102.e4. doi: 10.1016/j.jpeds.2018.08.079. Epub 2018 Oct 15.
2
Relationship Between Duration of Tube Feeding and Success of Oral Feeding in Preterm Infants.早产婴儿管饲持续时间与经口喂养成功率之间的关系
J Obstet Gynecol Neonatal Nurs. 2018 Sep;47(5):620-631. doi: 10.1016/j.jogn.2018.06.002. Epub 2018 Jul 21.
3
Feasibility of transferring intensive cared preterm infants from incubator to open crib at 1600 grams.
将 1600 克重症监护早产儿从保温箱转移到开放式婴儿床的可行性。
Ital J Pediatr. 2014 May 3;40:41. doi: 10.1186/1824-7288-40-41.
4
Weight at weaning of preterm infants from incubator to bassinet: a randomized clinical trial.早产儿从暖箱过渡到婴儿床时的断奶体重:一项随机临床试验。
Am J Perinatol. 2014 Jun;31(6):535-40. doi: 10.1055/s-0033-1354563. Epub 2013 Sep 2.
5
Transferring preterm infants from incubators to open cots at 1600 g: a multicentre randomised controlled trial.将 1600 克以下的早产儿从培养箱转移到开放式婴儿床:一项多中心随机对照试验。
Arch Dis Child Fetal Neonatal Ed. 2012 Mar;97(2):F88-92. doi: 10.1136/adc.2011.213587. Epub 2011 Aug 3.
6
Early weaning from incubator and early discharge of preterm infants: randomized clinical trial.早离孵化器和早产儿早出院:随机临床试验。
Pediatrics. 2010 Sep;126(3):e651-6. doi: 10.1542/peds.2009-3005. Epub 2010 Aug 9.
7
Incubator weaning in preterm infants and associated practice variation.早产儿的暖箱撤离及相关实践差异
J Perinatol. 2009 Aug;29(8):570-4. doi: 10.1038/jp.2009.54. Epub 2009 May 21.
8
Calculating postnatal growth velocity in very low birth weight (VLBW) premature infants.计算极低出生体重(VLBW)早产儿的出生后生长速度。
J Perinatol. 2009 Sep;29(9):618-22. doi: 10.1038/jp.2009.55. Epub 2009 May 21.
9
Feasibility and safety of early transfer of premature infants from incubators to cots: a pilot study.早产儿从暖箱早期转至婴儿床的可行性与安全性:一项试点研究。
J Paediatr Child Health. 2005 Dec;41(12):659-62. doi: 10.1111/j.1440-1754.2005.00754.x.
10
Energy expenditure in infants weaned from a convective incubator.来自对流式保育箱的断奶婴儿的能量消耗。
Am J Perinatol. 2004 Jul;21(5):253-6. doi: 10.1055/s-2004-829866.