Jeong Yong Geun, Kim Tae Hyo, Lee Chang Min, Shim Ki Shik, Moon In Kyu, Lee Sang Il, Jung Woon Tae, Lee Ok Jae
Department of Internal Medicine and Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.
Korean J Gastroenterol. 2010 May;55(5):331-5. doi: 10.4166/kjg.2010.55.5.331.
Wegener's granulomatosis (WG) is a disease characterized by a granulomatous necrotizing vasculitis of small vessels. Although any organ systems can be involved, gastrointestinal involvement in WG is notably uncommon. We present a case of 67-year-old man who was admitted with abdominal pain and diarrhea lasting for 3 weeks. Colonoscopy and abdominal CT scan revealed vasculitis and multiple mesenteric lymphadenopathy. Jejunum and mesenteric lymph nodes biopsies confirmed limited form of WG. The present case indicates that WG might involve only gastrointestinal tract and the histological confirmation is important for diagnosis.
韦格纳肉芽肿(WG)是一种以小血管肉芽肿性坏死性血管炎为特征的疾病。尽管任何器官系统都可能受累,但WG累及胃肠道的情况明显少见。我们报告一例67岁男性患者,因腹痛和腹泻持续3周入院。结肠镜检查和腹部CT扫描显示血管炎和多发肠系膜淋巴结肿大。空肠和肠系膜淋巴结活检证实为局限性WG。本病例表明,WG可能仅累及胃肠道,组织学确诊对诊断很重要。