Faculty of Environmental Science, Babes-Bolyai University, Cluj-Napoca, Romania.
Health Phys. 2010 Sep;99(3):301-7. doi: 10.1097/HP.0b013e3181c03cde.
The objective of the present study was to assess the lung cancer risk induced by exposures to radon progeny of people living in some areas of Transylvania, Romania. Indoor radon concentrations were measured in 667 dwellings of Stei area, Cluj, Bistrita-Nasaud, Sibiu, and Alba counties. Measurements were performed using CR-39 track detectors, exposed for a minimum of 3 mo. Average annual radon concentrations were 232, 114, 71, 62, and 161 Bq m for Stei area, Cluj, Bistrita-Nasaud, Sibiu, and Alba, respectively. The linear risk model of Darby was used to simulate the dose-effect relationship and relative lung cancer risk at low doses of alpha particles specific to residential radon exposures. Predicted relative risks at the measured exposure levels, together with information on the total number of reported lung cancer deaths and the number of people living in these regions, enabled us to estimate the fraction of lung cancer cases in each area that is attributable to radon. These percentages are 16.67% for Stei area, 9.09% for Cluj, 5.66% for Bistrita-Nasaud, 4.76% for Sibiu, and 12.28% for Alba county among lifetime non-smokers. Assuming that the smoking rates are similar for the investigated regions (10.72% smokers among men and 5.95% among women), around 64 to 69% of the total number of annual lung cancer deaths, stratified by sex, would be attributed to radon and occur among smoking male population, and around 35 to 44% would be attributed to radon and occur among smoking female population.
本研究的目的是评估罗马尼亚特兰西瓦尼亚部分地区居民接触氡子体的肺癌风险。在克卢日、比斯特里察-讷瑟乌德、锡比乌和阿尔巴县的 667 处住宅中测量了室内氡浓度。使用 CR-39 径迹探测器进行测量，暴露时间至少为 3 个月。Stei 地区、克卢日、比斯特里察-讷瑟乌德、锡比乌和阿尔巴的年平均氡浓度分别为 232、114、71、62 和 161 Bq/m。使用达比的线性风险模型模拟了剂量-效应关系以及住宅氡暴露的α粒子特定低剂量的相对肺癌风险。在所测量的暴露水平下，预测的相对风险，以及关于报告的肺癌死亡总数和居住在这些地区的人数的信息，使我们能够估计每个地区归因于氡的肺癌病例数。这些百分比分别为 Stei 地区的 16.67%、克卢日的 9.09%、比斯特里察-讷瑟乌德的 5.66%、锡比乌的 4.76%和阿尔巴县的 12.28%，对于终身不吸烟者。假设调查地区的吸烟率相似（男性吸烟者为 10.72%，女性吸烟者为 5.95%），每年按性别分层的肺癌总死亡人数中，约有 64%至 69%归因于氡，发生在吸烟男性人群中，约有 35%至 44%归因于氡，发生在吸烟女性人群中。
