Beyoglu Eye Research and Training Hospital, Istanbul, Turkey.
Jpn J Ophthalmol. 2010 Jul;54(4):331-7. doi: 10.1007/s10384-010-0807-z. Epub 2010 Aug 11.
To evaluate the anatomical and functional outcomes of pars plana vitrectomy (PPV) in pseudophakic retinal detachment (RD) complicated with proliferative vitreoretinopathy (PVR) without previous scleral buckling (SB) or vitrectomy, both with and without triamcinolone acetonide (TA) assistance.
In this retrospective, interventional, comparative case series, 72 pseudophakic eyes with RD with PVR grade C1 or greater underwent PPV either with (group 1, n = 40) or without (group 2, n = 32) TA assistance. Eyes with a minimum of 6 months of follow-up were evaluated. Main outcome measures were reattachment, redetachment, complication rate, and changes in visual acuity (VA).
The mean follow-up period was 14.57 +/- 8.55 months. Single-surgery and final reattachment rates were 87.50% and 95% in group 1, and 78.12 % and 96.87% in group 2, (P = 0.349, P = 1.000). Redetachment rates were 12.50% in group 1 and 21.87% group 2 (P = 0.349). In both groups the mean VA increased significantly in postoperative week 1 and in all control visits (P< 0.001) with no difference in complication rate (P > 0.05).
In this study PPV with TA assistance resulted in a lower, albeit statistically insignificant, redetachment rate in the treatment of RD complicated with PVR compared to PPV without TA assistance in eyes without previous SB or PPV. Visual acuity improved in 72% of eyes in both groups. Intraoperative and postoperative complication rates were also similar.
评估未行巩膜扣带术(SB)或玻璃体切除术,伴有或不伴有曲安奈德(TA)辅助的增生性玻璃体视网膜病变(PVR)合并的后发性白内障视网膜脱离(RD)行单纯玻璃体切除术(PPV)的解剖和功能结果。
在这项回顾性、干预性、对照病例系列研究中,72 只伴有 PVR C1 或更高级别、未行 SB 或玻璃体切除术的后发性白内障 RD 眼接受了 PPV 治疗,其中 40 只眼(第 1 组)接受了 TA 辅助治疗,32 只眼(第 2 组)未接受 TA 辅助治疗。对至少随访 6 个月的眼进行评估。主要观察指标是再附着、再脱离、并发症发生率和视力(VA)变化。
平均随访时间为 14.57 ± 8.55 个月。第 1 组单次手术和最终再附着率分别为 87.50%和 95%,第 2 组分别为 78.12%和 96.87%(P = 0.349,P = 1.000)。第 1 组和第 2 组的再脱离率分别为 12.50%和 21.87%(P = 0.349)。在两组中,术后第 1 周和所有对照检查时 VA 均显著增加(P<0.001),并发症发生率无差异(P>0.05)。
在这项研究中,与未行 TA 辅助的 PPV 相比,TA 辅助的 PPV 治疗未行 SB 或 PPV 的伴有 PVR 的 RD ,其再脱离率较低,但无统计学意义。两组中有 72%的眼视力提高。术中及术后并发症发生率也相似。