Raţiu A, Navolan D, Spătariu I, Biriş M, Miculiţă M, Motoc A
V. Babes University of Medicine and Pharmacy, Timişoara School of Medicine, Department of Obstetrics and Gynecology.
Rev Med Chir Soc Med Nat Iasi. 2010 Apr-Jun;114(2):454-6.
to determine whether a negative single complete ultrasound (US) of the lower limbs veins is a safe and accurate diagnostic method to rule out deep venous thrombosis (DVT) in pregnancy.
We performed a prospective study on 87 consecutive pregnant women with clinical suspicion of DVT in "Dr. D. Popescu" Maternity, Timişoara, between January 2007 and December 2009. All cases were investigated by color duplex ultrasound. Those who were negative but with high clinical probability of DVT underwent MR venography, the rest with negative US findings did not received anticoagulant therapy and US was repeated after seven days. All were instructed about the signs and symptoms of DVT and asked to return at six weeks postpartum when they were questioned if presented any.
from the 87 women 30 (34.48%) were found positive and two (2.29%) had a high clinical suspicion of DVT. 55 (63.21%) with negative findings repeated the US exam after 7 days which remained negative. Only 43 (78.18%) returned for the 6 weeks postpartum visit and none of them experienced any thromboembolic event during follow-up.
A single complete color duplex ultrasonography of lower limbs veins appears to be a safe method to rule out the diagnosis of deep venous thrombosis in pregnant women and if negative is safe to withhold heparin therapy.
确定下肢静脉单次超声检查结果为阴性是否是排除妊娠期深静脉血栓形成（DVT）的一种安全且准确的诊断方法。
2007年1月至2009年12月期间，我们在蒂米什瓦拉的“D. 波佩斯库医生”妇产医院对87例临床怀疑患有DVT的连续孕妇进行了一项前瞻性研究。所有病例均采用彩色双功超声检查。超声检查结果为阴性但DVT临床可能性高的患者接受了磁共振静脉造影检查，其余超声检查结果为阴性的患者未接受抗凝治疗，并在7天后重复进行超声检查。所有患者均被告知DVT的体征和症状，并被要求在产后6周复诊时接受询问，看是否出现任何相关症状。
87名女性中，30例（34.48%）被发现为阳性，2例（2.29%）临床高度怀疑患有DVT。55例（63.21%）超声检查结果为阴性的患者在7天后重复进行了超声检查，结果仍为阴性。只有43例（78.18%）患者在产后6周进行了复诊，且在随访期间均未发生任何血栓栓塞事件。
下肢静脉单次完整的彩色双功超声检查似乎是排除孕妇深静脉血栓形成诊断的一种安全方法，若检查结果为阴性，则可安全地停用肝素治疗。
