Darwish Ahmed, Nasr Ayman O, El Hassan Lamya A, Fahal Ahmed H
P,O, Box 102, Department of Surgery, Faculty of Medicine, University of Khartoum, Sudan.
J Med Case Rep. 2010 Aug 11;4:267. doi: 10.1186/1752-1947-4-267.
Breast adenoma is common. However, in the setting of post-transplantation immune suppression it may be expressed differently.
A 35-year-old Sudanese woman, with a history of renal transplantation two and half years prior to presentation, was on a single immune suppression therapy in the form of cyclosporine-A since the transplantation. During a regular follow-up visit, she was noticed to have gingival hypertrophy and bilateral breast and axillary swellings. She underwent successful surgical resection of the bilateral fibroadenomas.
Cyclosporine-A therapy post renal transplantation is associated with an increased incidence of benign breast changes as fibroadenoma. Regular follow-up and appropriate selection of immunosuppressant therapy are essential in the post transplantation management of these patients.
乳腺腺瘤很常见。然而，在移植后免疫抑制的情况下，其表现可能有所不同。
一名35岁的苏丹女性，在就诊前两年半有肾移植史，自移植后一直采用环孢素A单一免疫抑制疗法。在一次常规随访中，发现她有牙龈增生以及双侧乳房和腋窝肿胀。她成功接受了双侧纤维腺瘤的手术切除。
肾移植后使用环孢素A治疗与纤维腺瘤等良性乳腺病变的发生率增加有关。定期随访和适当选择免疫抑制疗法对这些患者的移植后管理至关重要。
