Bull A R, Campbell M J
Department of Medical Statistics and Computing, Southampton General Hospital, UK.
Br J Radiol. 1991 Jun;64(762):510-5. doi: 10.1259/0007-1285-64-762-510.
In order to assess the psychological effect of mammographic screening, questionnaires (which included psychometric tests) were sent to 750 women at invitation and, 6 weeks after screening, to 420 women normal after the first mammograph, to 240 women normal after special assessment, and to 68 women normal after open biopsy. Increasing degree of the investigation was associated both with increasing frequency of breast self examination (10% were practising breast self-examination at least once a week before screening compared with 24% for women after special assessment and 35% of women who had had an open biopsy (p less than 0.001)), and with greater confidence that any malignancy in the breast would have been found. Psychometric scores showed no increase of general levels of anxiety or depression in the screened groups. For anxiety, percentages abnormal were 5, 4, 2 and 6 for the four groups, respectively, and for depression the percentages abnormal were 5, 4, 4 and 6, respectively; 10% of screened women were more anxious about having breast cancer as a result of the screening. At least 10% of women proceeding to open biopsy of benign lesions require professional counselling and support. Psychological ill effects were not detected by the psychometric test among women who did not proceed to this final investigation. Behavioural changes did suggest a raised awareness or fear of potential cancer among the screened population.
为了评估乳腺钼靶筛查的心理影响,向750名受邀女性发放了问卷(包括心理测量测试),并在筛查6周后,向首次钼靶检查结果正常的420名女性、经过特殊评估后正常的240名女性以及开放活检后正常的68名女性发放了问卷。调查程度的增加与乳房自我检查频率的增加相关(筛查前10%的女性每周至少进行一次乳房自我检查,而经过特殊评估的女性为24%,接受开放活检的女性为35%(p<0.001)),也与对乳房中任何恶性肿瘤都能被发现的更大信心相关。心理测量得分显示,筛查组的焦虑或抑郁总体水平没有增加。焦虑方面,四组异常百分比分别为5%、4%、2%和6%,抑郁方面,异常百分比分别为5%、4%、4%和6%;10%的接受筛查的女性因筛查而对患乳腺癌更加焦虑。至少10%进行良性病变开放活检的女性需要专业咨询和支持。在未进行最终检查的女性中,心理测量测试未检测到心理不良影响。行为变化确实表明筛查人群对潜在癌症的意识或恐惧有所提高。