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[硫代磷酰胺、其顺磁性类似物及亚胺氧基自由基对肿瘤细胞分裂的影响]

[Effect of thiophosphamide, its paramagnetic analogs and the iminoxyl radical on the division of tumor cells].

作者信息

Kiseleva E G, Konovalova N P

出版信息

Vopr Onkol. 1978;24(4):60-5.

PMID:207020
Abstract

The authors have studied the effect of thiophosphamide its paramagentic analogs and iminoxyl radical on cell reproduction of Ehrlich ascites tumor. It was shown that the effect of paramagnetic analogs is made up of a sum of injuries produced by ethylenimine and iminoxyl portions of molecules. One of the analogs involved proves to be more active than thiophosphamide.

摘要

作者研究了硫代磷酰胺及其顺磁类似物和亚胺氧基自由基对艾氏腹水瘤细胞增殖的影响。结果表明,顺磁类似物的作用是由分子中的乙撑亚胺和亚胺氧基部分产生的损伤总和构成。其中一种所涉及的类似物被证明比硫代磷酰胺更具活性。

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