Lose G
Department of Urology, Rigshospitalet, Copenhagen, Denmark.
Br J Urol. 1991 Jun;67(6):580-5. doi: 10.1111/j.1464-410x.1991.tb15219.x.
A probe which permits continuous measurement of the related values of pressure and cross-sectional area in the female urethra was used for a quantitative description of the adjunctive closure forces in terms of pressure and power generation during coughing and squeezing in 30 females with genuine stress incontinence (GSI). Measurements were performed at the bladder neck, midurethrally and distally in the urethra. A statistically significant decrease in power generation was found at the bladder neck and midurethrally during squeezing compared with the values in healthy females. During coughing the power generation was significantly decreased midurethrally and measurement of pressure generation revealed similar results. These findings indicate that the active closure mechanisms at the bladder neck and midurethra are significantly weakened in females with GSI. The results do not support the concept that impaired passive pressure transmission to the urethra is an important pathophysiological factor in GSI.
使用一种能够连续测量女性尿道压力和横截面积相关值的探头，对30名真性压力性尿失禁（GSI）女性在咳嗽和挤压时的辅助关闭力进行了压力和功率产生方面的定量描述。测量在膀胱颈、尿道中段和尿道远端进行。与健康女性相比，发现挤压时膀胱颈和尿道中段的功率产生有统计学意义的降低。咳嗽时，尿道中段的功率产生显著降低，压力产生的测量结果相似。这些发现表明，GSI女性膀胱颈和尿道中段的主动关闭机制明显减弱。结果不支持这样的概念，即向尿道的被动压力传递受损是GSI的一个重要病理生理因素。
