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糖尿病性黄斑水肿

Diabetic macular edema.

作者信息

Bandello Francesco, Battaglia Parodi Maurizio, Lanzetta Paolo, Loewenstein Anat, Massin Pascale, Menchini Francesca, Veritti Daniele

出版信息

Dev Ophthalmol. 2010;47:73-110. doi: 10.1159/000320075. Epub 2010 Aug 10.

DOI:10.1159/000320075
PMID:20703045
Abstract

Diabetic macular edema (DME), defined as a retinal thickening involving or approaching the center of the macula, represents the most common cause of vision loss in patients affected by diabetes mellitus. In the last few years, many diagnostic tools have been proven useful in the detection and the monitoring of the features characterizing DME. On the other hand, several therapeutic approaches can now be proposed on the basis of the DME-specific characteristics. The aim of the present chapter is to thoroughly delineate the clinical and morpho functional characteristics of DME and its current treatment perspectives. The pathogenesis and the course of DME require a complex approach with multidisciplinary intervention both at the systemic and local levels.

摘要

糖尿病性黄斑水肿(DME)定义为累及或接近黄斑中心的视网膜增厚,是糖尿病患者视力丧失的最常见原因。在过去几年中,许多诊断工具已被证明在检测和监测DME特征方面很有用。另一方面,现在可以根据DME的特定特征提出几种治疗方法。本章的目的是全面描述DME的临床和形态功能特征及其当前的治疗前景。DME的发病机制和病程需要在全身和局部层面采取多学科干预的复杂方法。

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1
Diabetic macular edema.糖尿病性黄斑水肿
Dev Ophthalmol. 2010;47:73-110. doi: 10.1159/000320075. Epub 2010 Aug 10.
2
Detailed analysis of retinal morphology in patients with diabetic macular edema (DME) randomized to ranibizumab or triamcinolone treatment.对随机接受雷珠单抗或曲安奈德治疗的糖尿病性黄斑水肿(DME)患者的视网膜形态进行详细分析。
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3
Diabetic Macular Edema.糖尿病性黄斑水肿
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5
Comparison of the magnitude and time course of macular thinning induced by different interventions for diabetic macular edema: implications for sequence of application.不同干预措施诱导糖尿病性黄斑水肿所致黄斑变薄的程度和时间进程比较:对应用顺序的启示
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6
Triple therapy of vitrectomy, intravitreal triamcinolone, and macular laser photocoagulation for intractable diabetic macular edema.玻璃体切除术、玻璃体内注射曲安奈德和黄斑激光光凝三联疗法治疗顽固性糖尿病性黄斑水肿。
Am J Ophthalmol. 2008 Aug;146(2):332-3; author reply 333. doi: 10.1016/j.ajo.2008.04.017.
7
Current treatment approaches in diabetic macular edema.糖尿病性黄斑水肿的当前治疗方法。
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8
Diabetic Macular Edema: Traditional and Novel Treatment.糖尿病性黄斑水肿:传统与新型治疗方法
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Predictive factors of outcome of selective retina therapy for diabetic macular edema.糖尿病性黄斑水肿选择性视网膜光凝治疗结局的预测因素。
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10
Early change of central macular thickness after intravitreous triamcinolone or bevacizumab in diabetic macular edema or retinal vein occlusion.糖尿病性黄斑水肿或视网膜静脉阻塞患者玻璃体内曲安奈德或贝伐单抗注射后中央黄斑厚度的早期变化。
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引用本文的文献

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Autonomous Screening for Diabetic Macular Edema Using Deep Learning Processing of Retinal Images.利用视网膜图像的深度学习处理对糖尿病性黄斑水肿进行自主筛查。
Ophthalmol Sci. 2025 Jan 31;5(4):100722. doi: 10.1016/j.xops.2025.100722. eCollection 2025 Jul-Aug.
2
Diabetic Macular Edema Management: A Review of Anti-Vascular Endothelial Growth Factor (VEGF) Therapies.糖尿病性黄斑水肿的管理:抗血管内皮生长因子(VEGF)疗法综述
Cureus. 2024 Jan 21;16(1):e52676. doi: 10.7759/cureus.52676. eCollection 2024 Jan.
3
Effect of intravitreal dexamethasone solution on the reduction of macular thickness in pseudophakic diabetic patients in a public hospital in Brazil: a randomized clinical trial.
玻璃体内注射地塞米松溶液对巴西一家公立医院假晶状体糖尿病患者黄斑厚度降低的影响:一项随机临床试验。
Clin Ophthalmol. 2019 Aug 9;13:1523-1531. doi: 10.2147/OPTH.S214329. eCollection 2019.
4
Effect of thiamine pyrophosphate on retinopathy induced by hyperglycemia in rats: A biochemical and pathological evaluation.硫胺素焦磷酸对大鼠高血糖诱导的视网膜病变的影响:生化与病理学评估
Indian J Ophthalmol. 2016 Jun;64(6):434-9. doi: 10.4103/0301-4738.187666.
5
Ocular Complications of Diabetes and Therapeutic Approaches.糖尿病的眼部并发症及治疗方法
Biomed Res Int. 2016;2016:3801570. doi: 10.1155/2016/3801570. Epub 2016 Mar 28.
6
Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy.氧化应激与表观遗传修饰在糖尿病视网膜病变发病机制中的作用
Prog Retin Eye Res. 2015 Sep;48:40-61. doi: 10.1016/j.preteyeres.2015.05.001. Epub 2015 May 12.
7
Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema: a meta-analysis of randomized controlled trials.雷珠单抗单药治疗或联合激光与单纯激光治疗糖尿病性黄斑水肿的随机对照试验的荟萃分析
PLoS One. 2014 Dec 26;9(12):e115797. doi: 10.1371/journal.pone.0115797. eCollection 2014.
8
Diabetic Retinopathy-Update on Prevention Techniques, Present Therapies, and New Leads.糖尿病视网膜病变——预防技术、现有治疗方法及新进展综述
US Ophthalmic Rev. 2014;7(1):54-58. doi: 10.17925/usor.2014.07.01.54.
9
[Navigated focal retinal laser therapy using the NAVILAS® system for diabetic macula edema].
Ophthalmologe. 2012 Jul;109(7):692-8. doi: 10.1007/s00347-012-2559-2.
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Visual and anatomical outcomes following vitrectomy for complications of diabetic retinopathy: the DRIVE UK study.糖尿病视网膜病变并发症玻璃体切割术后的视力和解剖学结果:DRIVE UK 研究。
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