Jindal N, Shanker V, Tegta G R, Gupta M, Verma G K
Departmentof Dermatology, Venereology and Leprology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
Indian J Lepr. 2009 Oct-Dec;81(4):173-9.
This retrospective study was done to determine the epidemiological and clinical profile of leprosy patients in a tertiary care centre, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India. In this study, we included patients registered from January 2004 to December 2008 with the urban leprosy clinic of our tertiary care centre. Data regarding demographic details, clinical features, treatment and complications was extracted from the records of the leprosy clinic. 163 patients attended the clinic during this period with male to female ratio of 3:1. Majority of patients (47.8%) were in the middle age group (20-40 years) and 13.49% patients were < 20 years of age. In the clinical disease spectrum, 53.98% patients were in the borderline spectrum followed by lepromatous leprosy (33.12%) and polar tuberculoid leprosy (5.52%). Pure neuritic and indeterminate leprosy accounted for 3.06% each. Histoid lesions were present in 7.4% of lepromatous leprosy patients. 9.2% patients had definite history of contact in the family or neighborhood. 28.22% patients were immigrants either from Nepal or adjoining states of Himachal Pradesh. Epidemiological studies and contact tracing can decrease the disease burden and morbidity associated with the disease. Multidrug therapy (MDT) helps preventing and reducing the disease progression, severity and disabilities.
本回顾性研究旨在确定印度喜马偕尔邦西姆拉英迪拉·甘地医学院三级医疗中心麻风病患者的流行病学和临床特征。在本研究中，我们纳入了2004年1月至2008年12月在我们三级医疗中心城市麻风病诊所登记的患者。从麻风病诊所的记录中提取了有关人口统计学细节、临床特征、治疗和并发症的数据。在此期间，163名患者就诊，男女比例为3:1。大多数患者（47.8%）处于中年组（20-40岁），13.49%的患者年龄小于20岁。在临床疾病谱中，53.98%的患者处于中间型谱，其次是瘤型麻风（33.12%）和结核样型麻风（5.52%）。纯神经炎型和未定类麻风各占3.06%。7.4%的瘤型麻风患者有组织样病变。9.2%的患者在家庭或邻里中有明确的接触史。28.22%的患者是来自尼泊尔或喜马偕尔邦毗邻邦的移民。流行病学研究和接触者追踪可以减轻与该疾病相关的疾病负担和发病率。多药联合化疗（MDT）有助于预防和减少疾病进展、严重程度和残疾。
