Department of Anaesthetics, University Hospital of North Staffordshire, Stoke-on-Trent, UK.
Int J Obstet Anesth. 2010 Oct;19(4):451-3. doi: 10.1016/j.ijoa.2010.05.004. Epub 2010 Aug 11.
Gitelman's syndrome is a rare autosomal recessive salt-losing renal tubulopathy characterised by hypomagnesaemia, hypocalciuria and secondary aldosteronism, which results in hypokalaemia and metabolic alkalosis. The syndrome is a variant of a group of renal diseases termed Bartter's syndrome. Diagnosis is based on clinical symptoms and biochemical abnormalities. Sources of information on Gitelman's syndrome in pregnancy are scarce and anaesthetic management is challenging. Close monitoring and supplementation of potassium and magnesium are required to avoid possible obstetric and life threatening complications for both mother and child.
格替曼氏综合征是一种罕见的常染色体隐性遗传性盐耗竭性肾小管疾病，其特征为低镁血症、尿钙减少和继发性醛固酮增多症，导致低钾血症和代谢性碱中毒。该综合征是一组称为巴特氏综合征的肾脏疾病的变体。诊断基于临床症状和生化异常。关于妊娠中格替曼氏综合征的信息来源稀缺，麻醉管理具有挑战性。需要密切监测和补充钾和镁，以避免母婴可能出现的产科和危及生命的并发症。
