The ANU Research Centre, Department of Obstetrics and Gynaecology, University College Cork, Cork University Maternity Hospital, Wilton, Cork.
Nephrol Dial Transplant. 2010 Apr;25(4):1338-40. doi: 10.1093/ndt/gfp688. Epub 2010 Jan 25.
Gitelman's syndrome (GS), a rare renal disorder, results in hypokalaemia, hypomagnesaemia, hypocalciuria and a metabolic alkalosis. It is unclear if an alteration in management is necessary or beneficial during pregnancy. A 32-year-old woman with GS was managed in her second pregnancy. Antenatally, the patient required 39 (principally day case) admissions to the hospital for intravenous (IV) therapy and received a cumulative total of 47 l of IV 0.9% saline solution, 47 doses of 20 mmol magnesium chloride and 46 doses of 80 mmol potassium chloride. She delivered a 2940-g female infant in excellent condition by caesarean section. We would suggest that close attention to maternal weight gain during pregnancy is an easily available clinical tool to assess adequacy of fluid and electrolyte repletion in this condition.
格蒂尔曼综合征（GS）是一种罕见的肾脏疾病，导致低钾血症、低镁血症、低钙尿和代谢性碱中毒。目前尚不清楚在怀孕期间是否需要或有益改变治疗方法。一名 32 岁患有 GS 的妇女在第二次怀孕期间接受了治疗。该患者在产前共需要 39 次（主要为日间病床）住院静脉（IV）治疗，总共接受了 47 升 IV 0.9%生理盐水、47 剂 20 mmol 氯化镁和 46 剂 80 mmol 氯化钾。她通过剖腹产分娩了一名 2940 克的女婴，情况良好。我们建议，密切关注孕妇在怀孕期间的体重增加是评估这种情况下液体和电解质补充充足的一种简单的临床工具。
