Shen Han-Jian, Zhu Guang-You
Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, PR China.
Fa Yi Xue Za Zhi. 2010 Jun;26(3):206-9.
Neurogenic erectile dysfunction (NED) commonly results from erectile nerve damage. Recent researches have focused on the preclinical study of stem cell-based therapies targeted at repairing and protecting nervi erigentes. In this paper, researches of NESCs, MDSCs, ASCs and MSCs in NED are reviewed. Early studies have demonstrated that stem cells and gene modified stem cells were effective to the therapy of ED, even likely to cure ED. Stem cells are expected to be applied in the clinical therapy of NED. Stem cells as a new therapy technique will bring up a new challenge in forensic clinical medicine.
神经源性勃起功能障碍(NED)通常由勃起神经损伤引起。最近的研究集中在针对修复和保护阴茎神经的干细胞疗法的临床前研究。本文综述了神经干细胞、骨髓间充质干细胞、脂肪干细胞和间充质干细胞在NED中的研究。早期研究表明,干细胞和基因修饰干细胞对勃起功能障碍的治疗有效,甚至有可能治愈勃起功能障碍。干细胞有望应用于NED的临床治疗。干细胞作为一种新的治疗技术将给法医临床医学带来新的挑战。