Jarjour L, Kletzky O A
Department of Obstetrics and Gynecology, Harbor-University of California Los Angeles Medical Center, Torrance 90509.
Fertil Steril. 1991 Aug;56(2):202-7.
To evaluate the reliability of transvaginal ultrasound (US) and human chorionic gonadotropin (hCG) levels in detecting early abnormalities and predicting outcome of pregnancy.
One hundred thirty-two patients were studied, of which 113 had an intrauterine pregnancy and 19 had an ectopic pregnancy (EP).
In 78 with singleton normal pregnancies, US revealed a normal crown-rump length, heart motion, and hCG levels between 1,000 to 107,000 mIU/mL. Of 16 patients with small crown-rump length, heart motion present, and normal hCG levels, 6 aborted and 10 reached term. Thus, 6 of 84 (7.14%) singleton with fetal heart motion aborted. Thirteen with small crown-rump and absent heart motion also aborted. All 8 with an empty gestational sac aborted. In 8, transvaginal US detected four twins, two triplets, and two quadruplets, whereas hCG was not discriminative. Transvaginal US revealed an empty uterus in 19 patients with an EP, whereas serum hCG varied between 37 and 10,500 mIU/mL.
A fetal crown-rump length compatible with gestational age and fetal heart motion seen by transvaginal US can predict a term pregnancy in greater than 90% of patients.
评估经阴道超声（US）和人绒毛膜促性腺激素（hCG）水平在检测早期异常及预测妊娠结局方面的可靠性。
对132例患者进行了研究，其中113例为宫内妊娠，19例为异位妊娠（EP）。
在78例单胎正常妊娠患者中，超声显示头臀长度正常、有胎心搏动，hCG水平在1000至107000 mIU/mL之间。16例头臀长度小但有胎心搏动且hCG水平正常的患者中，6例流产，10例足月分娩。因此，84例有胎心搏动的单胎妊娠中有6例（7.14%）流产。13例头臀长度小且无胎心搏动的患者也流产了。所有8例空孕囊患者均流产。在8例患者中，经阴道超声检测出4例双胞胎、2例三胞胎和2例四胞胎，而hCG则无法区分。经阴道超声显示19例异位妊娠患者子宫内为空，而血清hCG水平在37至10500 mIU/mL之间。
经阴道超声所见的与孕周相符的胎儿头臀长度和胎心搏动可在90%以上的患者中预测足月妊娠。
