Hospital Universitario 12 de Octubre, Madrid, Spain.
Clin Transl Oncol. 2010 Aug;12(8):574-5. doi: 10.1007/s12094-010-0556-y.
Unknown primary cancer (UPC) is a common clinical syndrome classically associated with a poor prognosis. Pathological examination including immunohistochemistry continues to be essential in tumour origin characterization, although in many cases primary tumour site remains unknown. Gene expression based analysis may offer important diagnostic information that could lead to therapeutic decisions.
不明原发肿瘤（UPC）是一种常见的临床综合征，通常与预后不良相关。包括免疫组织化学在内的病理检查对于肿瘤起源的特征描述仍然至关重要，尽管在许多情况下仍无法确定原发肿瘤部位。基于基因表达的分析可能提供重要的诊断信息，从而有助于治疗决策。
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